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的次生代谢产物:代谢与药用价值。 需注意,原英文文本表述不太完整规范,可能会影响准确理解其确切所指。

Secondary Metabolites of : Metabolism and Medicinal Value.

作者信息

Fu Chen-Chen, Xu Fa-Ying, Qian Yu-Chen, Koo Hoi-Lun, Duan Yi-Fan, Weng Geng-Min, Fan Tai-Ping, Chen Mo-Xian, Zhu Fu-Yuan

机构信息

Co-Innovation Center for Sustainable Forestry in Southern China and Key Laboratory of National Forestry and Grassland Administration on Subtropical Forest Biodiversity Conservation, College of Biology and the Environment, Nanjing Forestry University, Nanjing, China.

International Cultivar Registration Center for Osmanthus, College of Biology and the Environment, Nanjing Forestry University, Nanjing, China.

出版信息

Front Pharmacol. 2022 Jul 18;13:922204. doi: 10.3389/fphar.2022.922204. eCollection 2022.

DOI:10.3389/fphar.2022.922204
PMID:35924042
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9340074/
Abstract

(scientific name: (Thunb.) Lour.) is a species of the genus in the family Oleaceae, and it has a long history of cultivation in China. is edible and is well known for conferring a natural fragrance to desserts. This flowering plant has long been cultivated for ornamental purposes. Most contemporary literature related to focuses on its edible value and new species discovery, but the functional use of is often neglected. has many properties that are beneficial to human health, and its roots, stems, leaves, flowers and fruits have medicinal value. These characteristics are recorded in the classics of traditional Chinese medicine. Studies on the metabolites and medicinal value of published in recent years were used in this study to evaluate the medicinal value of . Using keywords such as metabolites and , a systematic and nonexhaustive search of articles, papers and books related to the medicinal use of metabolites was conducted. Fifteen metabolites were identified through this literature search and classified into three categories according to their properties and structure: flavonoids, terpenes and phenolic acids. It was found that the pharmacological activities of these secondary metabolites mainly include antioxidant, anticancer, anti-inflammatory and antibacterial activities and that these metabolites can be used to treat many human diseases, such as cancer, skin diseases, cardiovascular diseases, and neurological diseases. Most of the reports that are currently available and concern the secondary metabolites of have limitations. Some reports introduce only the general classification of compounds in , and some reports introduce only a single compound. In contrast, the introduction section of this paper includes both the category and the functional value of each compound. While reviewing the data for this study, the authors found that the specific action sites of these compounds and their mechanisms of action in plants are relatively weak, and in the future, additional research should be conducted to investigate this topic further.

摘要

(学名:(Thunb.) Lour.)是木犀科属的一种植物,在中国有着悠久的栽培历史。它可食用,以赋予甜点天然香味而闻名。这种开花植物长期以来一直用于观赏栽培。大多数与相关的当代文献都集中在其食用价值和新物种发现上,但的功能用途却常常被忽视。具有许多对人体健康有益的特性,其根、茎、叶、花和果实都有药用价值。这些特性在中国传统医学典籍中均有记载。本研究采用近年来发表的关于的代谢产物和药用价值的研究来评估的药用价值。使用代谢产物等关键词,对与代谢产物药用相关的文章、论文和书籍进行了系统但非详尽的搜索。通过文献检索鉴定出15种代谢产物,并根据其性质和结构分为三类:黄酮类、萜类和酚酸类。研究发现,这些次生代谢产物的药理活性主要包括抗氧化、抗癌、抗炎和抗菌活性,并且这些代谢产物可用于治疗多种人类疾病,如癌症、皮肤病、心血管疾病和神经疾病。目前现有的大多数关于的次生代谢产物的报道都有局限性。一些报道仅介绍了中的化合物的一般分类,一些报道仅介绍了单一化合物。相比之下,本文的引言部分既包括了每种化合物的类别,也包括了其功能价值。在审查本研究的数据时,作者发现这些化合物在植物中的具体作用位点及其作用机制相对薄弱,未来应开展更多研究以进一步探讨这一主题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cdf/9340074/cd2a184ced92/fphar-13-922204-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cdf/9340074/4258a2496420/fphar-13-922204-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cdf/9340074/14bdeabc8db3/fphar-13-922204-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cdf/9340074/cd2a184ced92/fphar-13-922204-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cdf/9340074/4258a2496420/fphar-13-922204-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cdf/9340074/14bdeabc8db3/fphar-13-922204-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cdf/9340074/cd2a184ced92/fphar-13-922204-g003.jpg

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