Browder I W, Dowling J B, Koontz K K, Litwin M S
Ann Surg. 1987 Jun;205(6):649-58. doi: 10.1097/00000658-198706000-00006.
Since 1980, the authors have managed 19 patients with operative injuries to their biliary tracts. Eleven patients (58%) incurred their injuries during cholecystectomies for acute cholecystitis (average age--56 years); seven patients (37%) received their injuries during elective cholecystectomies (average age--24 years); and in one patient (5%) the injury occurred during gastrectomy. In group I were eight patients in whom injuries were recognized and repaired intraoperatively during their initial operations. Seven of these patients (88%) had primary duct reanastomoses, and one patient had a choledochoduodenostomy. All healed without further surgery, and none later had cholangitis develop. In group II were 11 patients diagnosed and reoperated later after surgery (mean time until diagnosis, 12 days). Seven of these patients (64%) were managed with Roux-en-Y hepaticojejunostomies or choledochojejunostomies. Four patients had cholangitis develop after surgery: two had demonstrable anastomic stenosis and two had no stenosis. Three of these four patients (75%) who had cholangitis develop did not have stents used in their repairs. The overall mortality rate in this series of 19 patients was 11%. The major risk factors for biliary tract injury were the presence of acute cholecystitis and of anatomically small biliary ducts. For this latter reason, younger patients who had elective cholecystectomies were particularly at risk. In delayed repair, the use of internal stents appeared to be useful in preventing the later development of stenosis and/or cholangitis; however, recurrent cholangitis developed in two patients who did not have demonstrable anastomotic stenoses.
自1980年以来,作者共处理了19例胆道手术损伤患者。11例患者(58%)在急性胆囊炎胆囊切除术期间受伤(平均年龄56岁);7例患者(37%)在择期胆囊切除术期间受伤(平均年龄24岁);1例患者(5%)在胃切除术期间受伤。第一组有8例患者,其损伤在初次手术时术中被识别并修复。其中7例患者(88%)进行了胆管一期吻合,1例患者进行了胆总管十二指肠吻合术。所有患者均愈合,无需进一步手术,且术后均未发生胆管炎。第二组有11例患者,术后经诊断并再次手术(至诊断的平均时间为12天)。其中7例患者(64%)接受了Roux-en-Y肝空肠吻合术或胆总管空肠吻合术。4例患者术后发生胆管炎:2例有明显的吻合口狭窄,2例无狭窄。这4例发生胆管炎的患者中,有3例(75%)修复时未使用支架。这19例患者的总死亡率为11%。胆道损伤的主要危险因素是存在急性胆囊炎和解剖结构上较小的胆管。由于后一个原因,接受择期胆囊切除术的年轻患者尤其危险。在延迟修复中,使用内支架似乎有助于预防后期狭窄和/或胆管炎的发生;然而,2例无明显吻合口狭窄的患者发生了复发性胆管炎。