Aldabain Louay, Haddaden Metri, Farooqi Rehan, Alissa Malaz
Hospital Medicine, MedStar Good Samaritan Hospital, Baltimore, USA.
Internal Medicine, MedStar Union Memorial Hospital, Baltimore, USA.
Cureus. 2022 Jul 5;14(7):e26588. doi: 10.7759/cureus.26588. eCollection 2022 Jul.
Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, primarily affects the respiratory system. While coronaviruses are not a common cause of neurological disease, they have been reported to cause direct central nervous system infection, as well as presumed para-infectious disorders. Here we report a very rare case of SARS-CoV-2 infection presenting as Miller Fisher syndrome with positive anti-GQ1b antibodies in a patient with a history of Guillain-Barré syndrome, which was treated with IV immunoglobulin resulting in marked improvement in her symptoms. Thus, a high index of suspicion and meticulous observation are the cornerstones to identifying possible uncommon presentations of COVID-19.
2019冠状病毒病由严重急性呼吸综合征冠状病毒2引起,主要影响呼吸系统。虽然冠状病毒并非神经系统疾病的常见病因,但据报道它们可导致中枢神经系统直接感染以及疑似感染后疾病。在此,我们报告一例非常罕见的严重急性呼吸综合征冠状病毒2感染病例,该病例表现为米勒费雪综合征,抗GQ1b抗体呈阳性,患者有格林-巴利综合征病史,经静脉注射免疫球蛋白治疗后症状显著改善。因此,高度的怀疑指数和细致的观察是识别新型冠状病毒肺炎可能不常见表现的基石。