Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Special Hospital for Addiction Diseases, Belgrade, Serbia.
Medicine (Baltimore). 2022 Aug 5;101(31):e29699. doi: 10.1097/MD.0000000000029699.
The correlation between substance use and depression has been emphasized in the literature. Substance use disorders can also adversely affect the caregivers of drug-addicted persons. A cross-sectional study was conducted at the Special Hospital for Addiction Diseases in Belgrade in 2015 to analyze the characteristics, consequences, and health-related quality of life of drug users and their caregivers. The sample comprised 136 users of various substances, and 136 caregivers. A questionnaire on socio-demographic characteristics, the Short Form Health Survey 36 (SF-36), and Beck Depression Inventory were administered to all participants. According to multivariate logistic regression analysis, compared with caregivers, substance users were significantly more frequently male (P < .001), ≤ 39 years old (P < .001), and more frequently reported the use of sedatives (P = .009) and smoking (P < .001). Some level of depression was present in all participants, but severe forms were more frequent in substance users (P = .010). Among substance users, mean scores of SF-36 domains ranged from 56.62‒87.17, and among their caregivers, from 50.37‒75.07; however, the difference was significant only for the health change domain (P = .037), the score for which was lower in caregivers. Substance users suffered from more severe forms of depression compared to their caregivers, who had lower SF-36 scores in the domain of health change.
文献强调了物质使用与抑郁之间的相关性。物质使用障碍也会对吸毒者的照顾者产生不利影响。2015 年，在贝尔格莱德的成瘾疾病专科医院进行了一项横断面研究，以分析吸毒者及其照顾者的特征、后果和与健康相关的生活质量。该样本包括 136 名各种物质的使用者和 136 名照顾者。所有参与者都接受了一份关于社会人口特征的问卷、简短健康调查 36 项（SF-36）和贝克抑郁量表。根据多变量逻辑回归分析，与照顾者相比，物质使用者更频繁地为男性（P<.001）、≤39 岁（P<.001），更频繁地报告使用镇静剂（P=.009）和吸烟（P<.001）。所有参与者都存在一定程度的抑郁，但物质使用者中更频繁地出现严重抑郁（P=.010）。在物质使用者中，SF-36 各领域的平均得分为 56.62-87.17，而在他们的照顾者中，得分为 50.37-75.07；然而，只有健康变化领域的差异具有统计学意义（P=.037），照顾者的得分较低。与照顾者相比，物质使用者的抑郁程度更严重，而照顾者在健康变化领域的 SF-36 得分较低。
