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吸烟对多发性癌症和单发性肺癌患者生存率的影响。

Effects of Tobacco Smoking on the Survivability of Patients with Multiple Cancers and Single Lung Cancer.

机构信息

Faculty of Health Sciences, Department of Pulmonology, University of Warmia and Mazury in Olsztyn, 10-357 Olsztyn, Poland.

Department of Biopharmacy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Jurasza 2, 85-089 Bydgoszcz, Poland.

出版信息

Int J Environ Res Public Health. 2022 Jul 27;19(15):9179. doi: 10.3390/ijerph19159179.

Abstract

Lung cancer is the leading cause of death worldwide among men and women. Tobacco smoking is the number one risk factor for lung cancer. The aim of our study was to evaluate the survivability of patients with single lung cancer in relation to the survival time in patients with multiple neoplasms whose last neoplasm was a lung cancer. A retrospective analysis was con-ducted of data from medical histories of patients hospitalized at the Pulmonary Hospital in Olsztyn (Poland) from 2012 to 2017, with a lung cancer diagnosis as the first or subsequent cancer. The total longevity of women with diagnosed multiple cancers was found to be shorter than that of men: 67.60 years (SD: 7.77) and 69.91 years (SD: 7.97), respectively. Among the ex-smokers, the longevity of men (68.93 years) was longer than that of women (66.18 years). Survival time, counted from the diagnosis of both the first and subsequent cancer, was longer among patients with multiple cancers than among patients with single lung cancer ( = 0.000). Women's survivability was worse than men's in the case of multiple cancers and in the group of people who quit smoking ( = 0.037; = 0.000). To conclude, smoking tobacco affects the survival of patients with lung cancer. Smoking cessation improves overall survival.

摘要

肺癌是全球男性和女性的主要死亡原因。吸烟是肺癌的头号风险因素。我们的研究目的是评估单发肺癌患者的生存率与最后一个肿瘤为肺癌的多发性肿瘤患者的生存时间之间的关系。对 2012 年至 2017 年在波兰奥尔什丁肺病医院住院的患者的病历数据进行了回顾性分析,这些患者的肺癌诊断为首发或后续癌症。患有多发性癌症的女性总寿命比男性短:分别为 67.60 岁(SD:7.77)和 69.91 岁(SD:7.97)。在已戒烟者中,男性(68.93 岁)的寿命长于女性(66.18 岁)。从首发和后续癌症的诊断开始计算,多发性癌症患者的生存时间长于单发肺癌患者( = 0.000)。在多发性癌症和戒烟人群中,女性的生存率均差于男性( = 0.037; = 0.000)。总之,吸烟会影响肺癌患者的生存。戒烟可提高总生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9c9/9368588/69e450989d01/ijerph-19-09179-g001.jpg

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