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MRF-IUNet:基于改进型 Inception U-Net 的多分辨率融合脑肿瘤分割网络。

MRF-IUNet: A Multiresolution Fusion Brain Tumor Segmentation Network Based on Improved Inception U-Net.

机构信息

School of Medical Information, Wannan Medical College, Wuhu 241002, China.

Research Center of Health Big Data Mining and Applications, Wannan Medical College, Wuhu 241002, China.

出版信息

Comput Math Methods Med. 2022 Aug 4;2022:6305748. doi: 10.1155/2022/6305748. eCollection 2022.

DOI:10.1155/2022/6305748
PMID:35966244
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9371863/
Abstract

The automatic segmentation method of MRI brain tumors uses computer technology to segment and label tumor areas and normal tissues, which plays an important role in assisting doctors in the clinical diagnosis and treatment of brain tumors. This paper proposed a multiresolution fusion MRI brain tumor segmentation algorithm based on improved inception U-Net named MRF-IUNet (multiresolution fusion inception U-Net). By replacing the original convolution modules in U-Net with the inception modules, the width and depth of the network are increased. The inception module connects convolution kernels of different sizes in parallel to obtain receptive fields of different sizes, which can extract features of different scales. In order to reduce the loss of detailed information during the downsampling process, atrous convolutions are introduced in the inception module to expand the receptive field. The multiresolution feature fusion modules are connected between the encoder and decoder of the proposed network to fuse the semantic features learned by the deeper layers and the spatial detail features learned by the early layers, which improves the recognition and segmentation of local detail features by the network and effectively improves the segmentation accuracy. The experimental results on the BraTS (the Multimodal Brain Tumor Segmentation Challenge) dataset show that the Dice similarity coefficient (DSC) obtained by the method in this paper is 0.94 for the enhanced tumor area, 0.83 for the whole tumor area, and 0.93 for the tumor core area. The segmentation accuracy has been improved.

摘要

MRI 脑肿瘤的自动分割方法利用计算机技术对肿瘤区域和正常组织进行分割和标记,对辅助医生进行脑肿瘤的临床诊断和治疗具有重要作用。本文提出了一种基于改进的 inception U-Net 的多分辨率融合 MRI 脑肿瘤分割算法,命名为 MRF-IUNet(多分辨率融合 inception U-Net)。通过用 inception 模块替换 U-Net 中的原始卷积模块,增加了网络的宽度和深度。inception 模块将不同大小的卷积核并行连接,以获取不同大小的感受野,从而提取不同尺度的特征。为了减少下采样过程中详细信息的丢失,在 inception 模块中引入空洞卷积来扩展感受野。在提出的网络的编码器和解码器之间连接多分辨率特征融合模块,融合由更深层学习的语义特征和由早期层学习的空间细节特征,提高网络对局部细节特征的识别和分割能力,有效提高分割精度。在 BraTS(多模态脑肿瘤分割挑战赛)数据集上的实验结果表明,本文方法得到的增强肿瘤区域的 Dice 相似系数(DSC)为 0.94,整个肿瘤区域的 DSC 为 0.83,肿瘤核心区域的 DSC 为 0.93,分割精度得到了提高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/ef0b98f3fd9c/CMMM2022-6305748.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/e947b2a5ee45/CMMM2022-6305748.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/3ba9278c93fc/CMMM2022-6305748.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/4959106d89c8/CMMM2022-6305748.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/8205d2fa879b/CMMM2022-6305748.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/464acfd750b3/CMMM2022-6305748.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/ef0b98f3fd9c/CMMM2022-6305748.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/e947b2a5ee45/CMMM2022-6305748.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/3ba9278c93fc/CMMM2022-6305748.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/4959106d89c8/CMMM2022-6305748.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/8205d2fa879b/CMMM2022-6305748.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/464acfd750b3/CMMM2022-6305748.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50f2/9371863/ef0b98f3fd9c/CMMM2022-6305748.006.jpg

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本文引用的文献

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Deep Learning Techniques for Medical Image Segmentation: Achievements and Challenges.深度学习技术在医学图像分割中的应用:成就与挑战。
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