Suppr超能文献

52种条纹鲶鱼ATP结合盒(ABC)转运蛋白基因的全基因组鉴定、特征分析及系统发育分析

Genome-Wide Identification, Characterisation and Phylogenetic Analysis of 52 Striped Catfish () ATP-Binding Cassette (ABC) Transporter Genes.

作者信息

Lim Leonard Whye Kit, Chung Hung Hui, Gan Han Ming

机构信息

Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia.

GeneSEQ Sdn Bhd, Bukit Beruntung, 48300 Rawang, Selangor, Malaysia.

出版信息

Trop Life Sci Res. 2022 Jul;33(2):257-293. doi: 10.21315/tlsr2022.33.2.12. Epub 2022 Jul 15.

Abstract

The (striped or tra catfish) is a Pangasiidae family member famous for its high unsaturated fatty acid content flesh. This riverine catfish can breathe in the air unlike the channel catfish. One of the most well-known ecotoxicological protein superfamily, the ATP-binding cassette (ABC) transporters, has been characterised in channel catfish through a genome-wide approach. Therefore, it is interesting to unearth these proteins within the striped catfish genome for a comprehensive comparison across all catfishes available. A total of 52 ABC transporters were discovered from the striped catfish genome. The motif analysis has unconcealed various unshared characteristics of some catfishes. The phylogenetic analysis has evidenced its effectiveness in the successful annotations of these transporter proteins. Duplicated genes such as ABCA1, ABCB3, ABCB6, ABCC5, ABCD3, ABCE1, ABCF2 as well as ABCG2 were uncovered within the striped and channel catfish genomes. This entire set of ABC transporters yields precious genomic data for future ecotoxicological, biochemical and physiological research in striped catfish.

摘要

(条纹鲶鱼或斑鲶)是芒鲶科的一员,以其富含高不饱和脂肪酸的鱼肉而闻名。这种河鲶与沟鲶不同,它可以在空气中呼吸。三磷酸腺苷结合盒(ABC)转运蛋白是最著名的生态毒理学蛋白超家族之一,已通过全基因组方法在沟鲶中得到表征。因此,在条纹鲶鱼基因组中挖掘这些蛋白质,以便对所有现有鲶鱼进行全面比较,是很有趣的。从条纹鲶鱼基因组中总共发现了52种ABC转运蛋白。基序分析揭示了一些鲶鱼的各种独特特征。系统发育分析证明了其在成功注释这些转运蛋白方面的有效性。在条纹鲶鱼和沟鲶基因组中发现了重复基因,如ABCA1、ABCB3、ABCB6、ABCC5、ABCD3、ABCE1、ABCF2以及ABCG2。这整套ABC转运蛋白为条纹鲶鱼未来的生态毒理学、生物化学和生理学研究提供了宝贵的基因组数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6932/9354906/c8b5089c3220/TLSR-33-2-257-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验