Hemamalini Nallaiah, Shanmugam Seerappalli Aran, Kathirvelpandian Ayyathurai, Deepak Agarwal, Kaliyamurthi Venkatachalam, Suresh Eswaran, Ezhilmathi Selvaram
Institute of Fisheries Post Graduate Studies, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Vaniyanchavadi, Chennai, Tamil Nadu 603103 India.
Present Address: PMFGR Centre, ICAR-National Bureau of Fish Genetic Resources, Kochi, Kerala 682018 India.
Indian J Microbiol. 2022 Sep;62(3):441-446. doi: 10.1007/s12088-022-01023-y. Epub 2022 Apr 25.
This study aims to determine the antimicrobial resistance (AMR) pattern in freshwater ornamental cyprinids, such as Goldfish and Tiger barb. Molecular characterization of bacterial isolates confirmed the presence of 7 bacterial isolates in Goldfish and 6 in Tiger barb. Antimicrobial susceptibility test using 36 antibiotics revealed a higher resistance pattern for bacitracin, rifampicin, trimethoprim, cefalexin, ampicillin, amoxicillin, nalidixic acid and nitrofurantoin. Sulphafurazole, norfloxacin and ciprofloxacin were effective against all the bacterial isolates derived from Goldfish and Tiger barb. Most bacterial isolates exhibited > 0.2 multi-drug resistance index (MDR), indicating the severity of antibiotic use in the culture system. The finding of the present study suggests that ornamental fish may act as the reservoir of MDR bacteria and dissemination of resistance genes to clinical and human commensal bacteria through horizontal gene transfer.
The online version contains supplementary material available at 10.1007/s12088-022-01023-y.
本研究旨在确定淡水观赏鲤科鱼类（如金鱼和虎皮鱼）中的抗菌药物耐药性（AMR）模式。对细菌分离株的分子特征分析证实金鱼中有7株细菌分离株，虎皮鱼中有6株。使用36种抗生素进行的药敏试验显示，杆菌肽、利福平、甲氧苄啶、头孢氨苄、氨苄西林、阿莫西林、萘啶酸和呋喃妥因的耐药性较高。磺胺异恶唑、诺氟沙星和环丙沙星对来自金鱼和虎皮鱼的所有细菌分离株均有效。大多数细菌分离株表现出>0.2的多重耐药指数（MDR），表明养殖系统中抗生素使用的严重性。本研究结果表明，观赏鱼可能是多重耐药细菌的储存库，并通过水平基因转移将耐药基因传播给临床和人类共生细菌。
在线版本包含可在10.1007/s12088-022-01023-y获取的补充材料。
