School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.
Department of Radiation Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Hum Vaccin Immunother. 2022 Nov 30;18(6):2102329. doi: 10.1080/21645515.2022.2102329. Epub 2022 Aug 17.
Patients with cancer are considered at high risk of COVID-19 related complications with higher mortality rates than healthy individuals. This study investigated the perception, acceptance, and influencing factors of COVID-19 vaccination among cancer patients in Guangzhou, China. A cross-sectional survey was conducted in Guangzhou, China from August to November 2021 in two tertiary medical centers. Outpatients were recruited through hospital posters to complete a questionnaire including demographics, medical history, knowledge, and attitude toward COVID-19 vaccines and COVID-19 vaccination status. Chi-square tests and multivariable logistic regression were used to analyze predictors for acceptance of COVID-19 vaccination. In total, only 75 out of 343 patients (21.87%) had received at least one dose of COVID-19 vaccine. Twenty-one patients (6.12%) had received a recommendation about COVID-19 vaccination from their physicians. Patients who were recommended by physicians to get vaccinated (aOR = 11.71 95% CI: 2.71-50.66), with a monthly income of more than CNY 5000 (aOR = 3.94, 95% CI: 1.88-8.26) were more likely to have received COVID-19 vaccination. Cancer patients who had been diagnosed for more than one year (aOR = 0.21, 95% CI: 0.09-0.51), had received multiple cancer treatment strategies (aOR = 0.34, 95% CI: 0.16-0.74), worried about the safety of COVID-19 vaccines (aOR = 0.21, 95% CI: 0.11-0.40), were less likely to have received COVID-19 vaccination. COVID-19 vaccination uptake among cancer patients was insufficient. The proportion of cancer patients receiving vaccination recommendations from physicians remains inadequate. Physicians are expected to play an essential role in patients' knowledge of the safety and effectiveness of COVID-19 vaccines.
癌症患者被认为感染 COVID-19 相关并发症的风险较高，死亡率高于健康人群。本研究调查了中国广州癌症患者对 COVID-19 疫苗的认知、接受程度和影响因素。2021 年 8 月至 11 月，在中国广州的两家三级医疗中心进行了一项横断面调查。通过医院海报招募门诊患者填写问卷，内容包括人口统计学、病史、对 COVID-19 疫苗的知识和态度以及 COVID-19 疫苗接种情况。采用卡方检验和多变量逻辑回归分析接受 COVID-19 疫苗接种的预测因素。总共只有 343 名患者中的 75 名（21.87%）接种了至少一剂 COVID-19 疫苗。21 名患者（6.12%）曾接受过医生关于 COVID-19 疫苗接种的建议。被医生建议接种疫苗的患者（aOR=11.71，95%CI：2.71-50.66），月收入超过 CNY 5000 元（aOR=3.94，95%CI：1.88-8.26）的患者更有可能接种 COVID-19 疫苗。已确诊超过一年的癌症患者（aOR=0.21，95%CI：0.09-0.51）、接受过多种癌症治疗策略的患者（aOR=0.34，95%CI：0.16-0.74）、担心 COVID-19 疫苗安全性的患者（aOR=0.21，95%CI：0.11-0.40）更不可能接种 COVID-19 疫苗。癌症患者 COVID-19 疫苗接种率不足。接受医生接种建议的癌症患者比例仍然不足。预计医生将在患者了解 COVID-19 疫苗的安全性和有效性方面发挥重要作用。
