2020 年 COVID-19 大流行期间澳大利亚人的健康相关生活质量：与大流行前数据的比较以及与不良结局相关的因素。
Health-related quality of life of Australians during the 2020 COVID-19 pandemic: a comparison with pre-pandemic data and factors associated with poor outcomes.
机构信息
NHMRC Clinical Trials Centre, The University of Sydney, Sydney, Australia.
Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
出版信息
Qual Life Res. 2023 Feb;32(2):339-355. doi: 10.1007/s11136-022-03222-y. Epub 2022 Aug 22.
PURPOSE
Compare the health-related quality of life (HRQL) of the Australian general population during the COVID-19 pandemic (2020) with pre-pandemic data (2015-2016) and identify pandemic-related and demographic factors associated with poorer HRQL.
METHODS
Participants were quota sampled from an online panel by four regions (defined by active COVID-19 case numbers); then by age and sex. Participants completed an online survey about their HRQL [EORTC QLQ-C30 questionnaire and General Health Question (GHQ)], demographic characteristics, and the impact of the pandemic on daily life. HRQL scores were compared to a 2015-2016 reference sample using independent t-tests, adjusted for multiple testing. Associations between 22 pre-specified factors (pandemic-related and demographic) and 15 QLQ-C30 domains and GHQ, were assessed with multiple regressions.
RESULTS
Most domains were statistically significantly worse for the 2020 sample (n = 1898) compared to the reference sample (n = 1979), except fatigue and pain. Differences were largest for the youngest group (18-29 years) for cognitive functioning, nausea, diarrhoea, and financial difficulties. Emotional functioning was worse for 2020 participants aged 18-59, but not for those 60 +. All models were statistically significant at p < .001; the most variance was explained for emotional functioning, QLQ-C30 global health/QOL, nausea/vomiting, GHQ, and financial difficulties. Generally, increased workload, negative COVID-19 impacts, COVID-19-related worries, and negative attitudes towards public health order compliance were associated with poorer HRQL outcomes.
CONCLUSION
During the COVID-19 pandemic, Australians reported poorer HRQL relative to a pre-pandemic sample. Risk factors for poor HRQL outcomes included greater negative pandemic-related impacts, poorer compliance attitudes, and younger age.
TRIAL REGISTRATION
ANZCTR number is: ACTRN12621001240831. Web address of your trial: https://www.anzctr.org.au/ACTRN12621001240831.aspx . Date submitted: 26/08/2021 2:56:53 PM. Date registered: 14/09/2021 9:40:31 AM. Registered by: Margaret-Ann Tait. Principal Investigator: Madeleine King.
目的
比较 2020 年（新冠大流行期间）澳大利亚普通人群的健康相关生活质量（HRQL）与大流行前（2015-2016 年）的数据，并确定与较差 HRQL 相关的大流行相关和人口统计学因素。
方法
参与者通过四个地区（根据活跃的 COVID-19 病例数定义）的在线小组进行配额抽样；然后根据年龄和性别进行抽样。参与者完成了一项关于他们的 HRQL [EORTC QLQ-C30 问卷和一般健康问题 (GHQ)]、人口统计学特征以及大流行对日常生活影响的在线调查。使用独立 t 检验将 HRQL 评分与 2015-2016 年的参考样本进行比较，并对多次检验进行了调整。使用多元回归评估 22 个预先指定的因素（与大流行相关和人口统计学相关）与 15 个 QLQ-C30 域和 GHQ 之间的关联。
结果
与参考样本（n=1979）相比，2020 年样本（n=1898）的大多数领域的 HRQL 评分均存在统计学显著差异，除疲劳和疼痛外。对于年龄最小的组（18-29 岁），认知功能、恶心、腹泻和经济困难的差异最大。2020 年 18-59 岁的参与者的情绪功能更差，但 60 岁以上的参与者则没有。所有模型均在 p<0.001 时具有统计学意义；解释了最大方差的是情绪功能、QLQ-C30 总体健康/生活质量、恶心/呕吐、GHQ 和经济困难。通常，工作量增加、COVID-19 负面影响增加、对 COVID-19 相关担忧以及对公共卫生秩序合规性的消极态度与较差的 HRQL 结果相关。
结论
在 COVID-19 大流行期间，澳大利亚人报告称，与大流行前样本相比，他们的 HRQL 较差。较差的 HRQL 结果的风险因素包括更大的负面大流行相关影响、较差的合规态度和更年轻的年龄。
试验注册
ANZCTR 编号为：ACTRN12621001240831。您的试验网址：https://www.anzctr.org.au/ACTRN12621001240831.aspx。提交日期：2021 年 8 月 26 日，下午 2:56:53。注册日期：2021 年 9 月 14 日，上午 9:40:31。注册人：Margaret-Ann Tait。主要研究者：Madeleine King。
Zotero 插件