Liu Sha, Zhao Kaixuan, Huang Meiyuan, Zeng Meimei, Deng Yan, Li Song, Chen Hui, Li Wen, Chen Zhu
Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Department of Pathology, Central South University, Zhuzhou, China.
Front Bioeng Biotechnol. 2022 Aug 8;10:958134. doi: 10.3389/fbioe.2022.958134. eCollection 2022.
The global burden of foodborne disease is enormous and foodborne pathogens are the leading cause of human illnesses. The detection of foodborne pathogenic bacteria has become a research hotspot in recent years. Rapid detection methods based on immunoassay, molecular biology, microfluidic chip, metabolism, biosensor, and mass spectrometry have developed rapidly and become the main methods for the detection of foodborne pathogens. This study reviewed a variety of rapid detection methods in recent years. The research advances are introduced based on the above technical methods for the rapid detection of foodborne pathogenic bacteria. The study also discusses the limitations of existing methods and their advantages and future development direction, to form an overall understanding of the detection methods, and for point-of-care testing (POCT) applications to accurately and rapidly diagnose and control diseases.
食源性疾病的全球负担巨大,食源性病原体是人类疾病的主要原因。近年来,食源性病原体的检测已成为研究热点。基于免疫分析、分子生物学、微流控芯片、代谢、生物传感器和质谱的快速检测方法发展迅速,成为食源性病原体检测的主要方法。本研究综述了近年来的多种快速检测方法。基于上述食源性病原体快速检测技术方法介绍了研究进展。该研究还讨论了现有方法的局限性及其优势和未来发展方向,以形成对检测方法的全面认识,并用于即时检测(POCT)应用,以准确、快速地诊断和控制疾病。