Applied Microbiology Laboratory, Department of Forestry, North Eastern Regional Institute of Science and Technology, Nirjuli 791109, India.
Department of Botany, University of Lucknow, Lucknow 226007, India.
Toxins (Basel). 2022 Jul 31;14(8):527. doi: 10.3390/toxins14080527.
Mycotoxins are secondary metabolites produced by fungi that infect a wide range of foods worldwide. Nivalenol (NIV), a type B trichothecene produced by numerous species, has the ability to infect a variety of foods both in the field and during post-harvest handling and management. NIV is frequently found in cereal and cereal-based goods, and its strong cytotoxicity poses major concerns for both human and animal health. To address these issues, this review briefly overviews the sources, occurrence, chemistry and biosynthesis of NIV. Additionally, a brief overview of several sophisticated detection and management techniques is included, along with the implications of processing and environmental factors on the formation of NIV. This review's main goal is to offer trustworthy and current information on NIV as a mycotoxin concern in foods, with potential mitigation measures to assure food safety and security.
真菌产生的次生代谢物即为霉菌毒素，其广泛存在于世界各地的各类食物中。雪腐镰刀菌烯醇（NIV）是一种 B 型单端孢霉烯族毒素，由多种真菌产生，具有在田间和收获后处理与管理过程中感染多种食物的能力。NIV 常存在于谷物及其制品中，其强烈的细胞毒性对人类和动物健康构成了重大威胁。为了解决这些问题，本文简要概述了 NIV 的来源、发生、化学性质和生物合成。此外，本文还简要概述了几种复杂的检测和管理技术，以及加工和环境因素对 NIV 形成的影响。本文的主要目的是提供有关 NIV 作为食品中霉菌毒素的可靠且最新的信息，以及潜在的缓解措施，以确保食品安全。
