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欧洲对哺乳期临床乳腺炎治疗的不同观点。

Different European Perspectives on the Treatment of Clinical Mastitis in Lactation.

作者信息

Preine Franziska, Herrera Demetrio, Scherpenzeel Christian, Kalmus Piret, McCoy Finola, Smulski Sebastian, Rajala-Schultz Päivi, Schmenger Anne, Moroni Paolo, Krömker Volker

机构信息

Department of Bioprocess Engineering, Microbiology, Faculty II, Hannover University of Applied Sciences and Arts, 30453 Hannover, Germany.

Veterinary Services Company Q-Llet SLP, 08553 Barcelona, Spain.

出版信息

Antibiotics (Basel). 2022 Aug 16;11(8):1107. doi: 10.3390/antibiotics11081107.

DOI:10.3390/antibiotics11081107
PMID:36009976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9404852/
Abstract

As part of the European Network for Optimization of Veterinary Antimicrobial Treatment (ENOVAT), a webinar on the topic "Mastitis Treatment in Lactation" was held, in which eight mastitis experts from different European countries (Spain, The Netherlands, Estonia, Ireland, Poland, Finland, Germany, and Italy) presented their treatment approaches for clinical mastitis in lactation. The aim of this study was to compare the therapeutic approaches to identify commonalities and differences. In all eight participating countries, the decision to start treatment is usually made by the veterinarians, while the farm personnel are responsible for treatment administration. Antibiotic treatment is then typically administered intramammarily. The treatment duration often depends on the label instructions and is frequently extended if or is involved. Administering supportive therapy, especially non-steroidal anti-inflammatory drugs (NSAIDs) is an established practice in all countries. Penicillin is the first-choice drug for the treatment of mastitis in an increasing number of countries. The use of critically important antimicrobials (CIAs) such as quinolones and third- and fourth-generation cephalosporins is at a low level in Finland and The Netherlands. In Estonia, Germany, Italy, and Spain, the use of CIAs is declining and is only allowed if milk samples are analyzed in advance following the legal framework. Systems for monitoring antibiotic use are being introduced in more and more countries. This exchange of different views will help the European countries to move towards a common high standard of antimicrobial stewardship in veterinary medicine.

摘要

作为欧洲兽医抗菌治疗优化网络(ENOVAT)的一部分,举办了一场关于“哺乳期乳腺炎治疗”主题的网络研讨会,来自不同欧洲国家(西班牙、荷兰、爱沙尼亚、爱尔兰、波兰、芬兰、德国和意大利)的八位乳腺炎专家介绍了他们针对哺乳期临床乳腺炎的治疗方法。本研究的目的是比较这些治疗方法,以找出共同点和差异。在所有八个参与国家中,开始治疗的决定通常由兽医做出,而农场工作人员负责治疗的实施。然后通常通过乳房内给药进行抗生素治疗。治疗持续时间通常取决于标签说明,如果涉及[此处原文缺失相关内容],则经常会延长。在所有国家,给予支持性治疗,尤其是非甾体抗炎药(NSAIDs)都是既定做法。在越来越多的国家,青霉素是治疗乳腺炎的首选药物。在芬兰和荷兰,喹诺酮类以及第三代和第四代头孢菌素等 critically important antimicrobials(CIA,此处原文可能有误,推测为“重要抗菌药物”)的使用水平较低。在爱沙尼亚、德国、意大利和西班牙,重要抗菌药物的使用正在下降,并且只有在按照法律框架提前对牛奶样本进行分析的情况下才允许使用。越来越多的国家正在引入抗生素使用监测系统。这种不同观点的交流将有助于欧洲国家朝着兽医抗菌药物管理的共同高标准迈进。

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