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单体从 CAD-CAM 材料和传统树脂复合材料在蒸馏水中和人工唾液中的洗脱。

Elution of Monomers From CAD-CAM Materials and Conventional Resin Composite in Distilled Water and Artificial Saliva.

机构信息

*Petros Mourouzis, MSc, PhD, assistant professor, Department of Operative Dentistry, Division of Dental Tissues Pathology and Therapeutics, Faculty of Dentistry, Aristotle University of Thessaloniki, Greece.

Ellisavet-Ioanna Diamantopoulou, MSc, Department of Chemistry, Laboratory of Analytical Chemistry, Aristotle University of Thessaloniki, Greece.

出版信息

Oper Dent. 2022 Sep 1;47(5):E241-E252. doi: 10.2341/21-079-L.

Abstract

PURPOSE

The purpose of this study was to evaluate the leaching pattern of different types of polymer computer-aided design and computer-aided manufacturing (CAD-CAM) materials with a conventional resin composite.

METHODS AND MATERIALS

Specimens of three representatives by type of polymer CAD-CAM blocks and one conventional resin composite were suspended using a silk thread in distilled water and artificial saliva. After one day, seven days, 14 days, 30 days, and 60 days, the analysis of the eluates for the detection of bisphenol A (BPA), urethane dimethacrylate (UDMA), triethylene glycol dimethacrylate (TEGDMA) and bisphenol A-glycidyl dimethacrylate (Bis-GMA) was quantified by utilizing high-performance liquid chromatography (HPLC).

RESULTS

TEGDMA was the main eluted monomer for the polymer CAD-CAM materials for both solutions. However, there was a decreasing pattern throughout the tested period. On the contrary, there was a constant release of monomers from the conventional resin composite. Bisphenol-A was released only by the conventional resin composite and in both solutions chosen.

CONCLUSIONS

Different types of polymer CAD-CAM materials release minimal or no monomers compared to the conventional resin composite material. The methods of fabrication of polymer CAD-CAM materials produces better properties than the conventional resin composite with a dramatic decrease of monomer elution.

摘要

目的

本研究旨在评估不同类型的聚合物计算机辅助设计和计算机辅助制造(CAD-CAM)材料与传统树脂复合材料的浸出模式。

方法和材料

使用丝线将三种类型的聚合物 CAD-CAM 块和一种传统树脂复合材料的代表试件悬挂在蒸馏水中和人工唾液中。在第 1 天、第 7 天、第 14 天、第 30 天和第 60 天,通过高效液相色谱法(HPLC)定量分析浸出液中双酚 A(BPA)、尿烷二甲基丙烯酸酯(UDMA)、三乙二醇二甲基丙烯酸酯(TEGDMA)和双酚 A-缩水甘油二甲基丙烯酸酯(Bis-GMA)的含量。

结果

在两种溶液中,TEGDMA 是聚合物 CAD-CAM 材料的主要洗脱单体。然而,在整个测试期间,其洗脱量呈下降趋势。相反,从传统树脂复合材料中不断释放出单体。只有传统树脂复合材料在两种选择的溶液中释放出双酚-A。

结论

与传统树脂复合材料相比,不同类型的聚合物 CAD-CAM 材料释放的单体较少或没有。聚合物 CAD-CAM 材料的制造方法比传统树脂复合材料具有更好的性能,单体的洗脱量显著减少。

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