Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, 755-8505, Japan.
Clinical Research Center, Yamaguchi University Hospital, Ube, Yamaguchi, 755-8505, Japan.
Sci Rep. 2022 Aug 26;12(1):14630. doi: 10.1038/s41598-022-18299-1.
We evaluated the early effects of pars plana vitrectomy (PPV) on corneal biomechanics by comparing corneal hysteresis (CH) after cataract surgery (phacoemulsification and aspiration with intraocular lens implantation; PEA + IOL) alone and PPV combined with cataract surgery. This study included 20 eyes (18 patients), who underwent cataract surgery alone (PEA + IOL group), and 28 eyes (27 patients) who underwent PPV combined with cataract surgery (PPV triple group). The CH was 11.1 ± 1.1, 10.4 ± 1.1, and 11.0 ± 1.0 mmHg in the PEA + IOL group and 11.0 ± 1.4, 9.8 ± 1.4, and 10.6 ± 1.6 mmHg in the PPV triple group, preoperatively, at 2 weeks, and 3 months after surgery, respectively. The CH was not significantly different after surgery in the PEA + IOL group, but decreased significantly in the PPV triple group 2 weeks following surgery (p < 0.01). Intraocular pressure (IOP) and central corneal thickness (CCT) did not change significantly after surgery in either group. Preoperatively, there was a positive correlation between CH and CCT in the PPV triple group, but the correlation disappeared postoperatively. In PPV combined with cataract surgery, CH temporarily decreased postoperatively, independent of IOP and CCT. Removal of the vitreous may reduce the elasticity and rigidity of the entire eye.
我们通过比较单纯白内障手术(超声乳化白内障吸除联合人工晶状体植入术;PEA+IOL)后和玻璃体切割术联合白内障手术后的角膜滞后(CH),评估了经平坦部玻璃体切除术(PPV)对角膜生物力学的早期影响。本研究纳入了 20 只眼(18 例患者),行单纯白内障手术(PEA+IOL 组),以及 28 只眼(27 例患者)行 PPV 联合白内障手术(PPV 三联组)。PEA+IOL 组术前、术后 2 周和 3 个月的 CH 分别为 11.1±1.1mmHg、10.4±1.1mmHg 和 11.0±1.0mmHg,PPV 三联组分别为 11.0±1.4mmHg、9.8±1.4mmHg 和 10.6±1.6mmHg。PEA+IOL 组术后 CH 无显著差异,但 PPV 三联组术后 2 周 CH 显著降低(p<0.01)。两组术后眼压(IOP)和中央角膜厚度(CCT)均无显著变化。术前,PPV 三联组 CH 与 CCT 呈正相关,但术后相关性消失。在 PPV 联合白内障手术中,CH 术后暂时降低,与 IOP 和 CCT 无关。玻璃体切除可能会降低整个眼球的弹性和刚性。