迁移、婚姻状况和吸烟作为癌症的风险决定因素。

Migration, marital status and smoking as risk determinants of cancer.

作者信息

Tenkanen L, Teppo L

出版信息

Scand J Soc Med. 1987;15(2):67-72. doi: 10.1177/140349488701500203.

Abstract

To study the importance of migration to urban area, marital status and smoking as risk factors in cancer, a cohort of 4,475 Finnish men was followed up for the occurrence of cancer during the period 1964-1980. Of particular interest was the interaction of migration or marital status with smoking. For cancers at all sites, not married urbanized smoking men had the greatest risk, followed by not married native urban smokers. This pattern was mainly due to high risk of cancers of the lung and larynx among the urbanized men, with a risk peak among urbanized not married smokers. The pattern persisted even when the amount smoked was allowed for. The importance in lung cancer epidemiology of vitamin A deficiency, occupation and psychosocial stress was discussed, and some support was found for the role of psychosocial stress in both the migration and the marital status factors.

摘要

为研究移居城市、婚姻状况和吸烟作为癌症风险因素的重要性，对4475名芬兰男性组成的队列在1964年至1980年期间随访其癌症发生情况。特别令人感兴趣的是移居或婚姻状况与吸烟之间的相互作用。对于所有部位的癌症，未婚的移居吸烟男性风险最高，其次是未婚的本地城市吸烟者。这种模式主要是由于移居男性中肺癌和喉癌风险较高，在未婚的移居吸烟者中风险达到峰值。即使考虑吸烟量，这种模式依然存在。讨论了维生素A缺乏、职业和心理社会压力在肺癌流行病学中的重要性，并发现心理社会压力在移居和婚姻状况因素中发挥作用得到了一些支持。