Daniel Beniam, Agenagnew Liyew, Workicho Abdulhalik, Abera Mubarek
Department of Psychiatry, Jimma University, Jimma, Ethiopia.
Department of Epidemiology, Jimma University, Jimma, Ethiopia.
Neuropsychiatr Dis Treat. 2022 Aug 22;18:1789-1798. doi: 10.2147/NDT.S377430. eCollection 2022.
Cognition is one of the most complex functions of the human brain, and major neurocognitive disorders affect this function causing a wide array of problems in an individual's life. Screening for major neurocognitive disorders can be helpful in designing and implementing early interventions.
This study was designed to assess the reliability and validity of the Montreal Cognitive Assessment (MoCA) tool to detect major neurocognitive disorders among older people in Ethiopia.
One hundred and sixteen randomly selected older adults in Ethiopia were involved in a cross-sectional study. The Diagnostic and Statistical Manual of Mental Disorders criteria for major neurocognitive disorders was used as a gold standard. Data were analyzed using STATA v16 statistical software. Receiver operating curve analysis was performed, and inter-rater, internal consistency reliabilities, content, criterion and construct validities were determined. Statistically significance was declared at a p-value of <0.05.
The study had a 100% response rate. The mean age of the study participants was 69.87 ± 7.8. The inter-rater reliability value was 0.96, and Cronbach's alpha was 0.79. The optimal cutoff value was ≤21, and Montreal Cognitive Assessment has an area under curve value of 0.89. The sensitivity, specificity, positive and negative likelihood ratios, and positive and negative predictive values of MoCA are 87.18%, 74.03%, 3.35, 0.17, 63%, and 91.9%, respectively. The tool also has good concurrent and construct validities.
The Montreal Cognitive Assessment tool was a reliable and valid tool to detect major neurocognitive disorder. It can be incorporated into the clinical and research practices in developing countries.
认知是人类大脑最复杂的功能之一，主要神经认知障碍会影响这一功能，给个人生活带来一系列问题。筛查主要神经认知障碍有助于设计和实施早期干预措施。
本研究旨在评估蒙特利尔认知评估（MoCA）工具在埃塞俄比亚老年人中检测主要神经认知障碍的可靠性和有效性。
埃塞俄比亚116名随机选取的老年人参与了一项横断面研究。以《精神疾病诊断与统计手册》中主要神经认知障碍的标准作为金标准。使用STATA v16统计软件进行数据分析。进行了受试者工作特征曲线分析，并确定了评分者间信度、内部一致性信度、内容效度、标准效度和结构效度。p值<0.05时具有统计学意义。
该研究的应答率为100%。研究参与者的平均年龄为69.87±7.8岁。评分者间信度值为0.96，Cronbach's α系数为0.79。最佳截断值为≤21，蒙特利尔认知评估的曲线下面积值为0.89。MoCA的敏感性、特异性、阳性似然比、阴性似然比、阳性预测值和阴性预测值分别为87.18%、74.03%、3.35、0.17、63%和91.9%。该工具还具有良好的同时效度和结构效度。
蒙特利尔认知评估工具是检测主要神经认知障碍的可靠且有效的工具。它可纳入发展中国家的临床和研究实践中。
