Jinlin Guo, Shaohui Song, Wenjun Zhang, Xinfeng Cai
Department of Pharmacy, Shanxi Provincial People's Hospital, Taiyuan, People's Republic of China.
Department of Pharmacy, The Maternal and Child Health Hospital of Dadukou District of Chongqing City, Chongqing, People's Republic of China.
Infect Drug Resist. 2022 Aug 25;15:4853-4857. doi: 10.2147/IDR.S379005. eCollection 2022.
We report a case of co-infection with , and due to tooth extraction in a mildly immunosuppressed patient. This patient did not respond well to a meropenem-based regimen, and the number of lesions was significantly reduced after switching to imipenem. The patient's trough concentration was insufficient when using conventional doses of voriconazole for the treatment of pulmonary aspergillosis. After adding omeprazole, the concentration reached standard levels and symptoms improved. The patient eventually made a full recovery.
我们报告了一例轻度免疫抑制患者因拔牙导致 、 和 共同感染的病例。该患者对基于美罗培南的治疗方案反应不佳,改用亚胺培南后病变数量显著减少。在使用常规剂量伏立康唑治疗肺曲霉病时,患者的谷浓度不足。添加奥美拉唑后,浓度达到标准水平且症状改善。患者最终完全康复。