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青少年使用大麻与抑郁症的发展:两者之间是否存在既定的线性关系?

Cannabis Use and the Development of Depression in Adolescents: Is There an Established Linear Relationship Between the Two?

作者信息

White Chantelle T, Shamim Humaira, Al Shouli Roba, Habbal Ahmad B, Mohammed Lubna

机构信息

Pediatrics, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Dermatology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

出版信息

Cureus. 2022 Jul 28;14(7):e27394. doi: 10.7759/cureus.27394. eCollection 2022 Jul.

DOI:10.7759/cureus.27394
PMID:36046299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9418628/
Abstract

The period of adolescence is a stage during which individuals experience several physical and psychological changes which increase their vulnerabilities to environmental influences. Cannabis exposure is one environmental factor that may put their health at risk. Various research agree that a connection exists between the onset of depression and cannabis use. Cannabis can affect the adolescents' brain, making them susceptible to depression. Depression is a disorder that manifests in a myriad of ways that can be detrimental to individuals. This problem is not only confined to the individuals themselves, but it is also a societal problem. The relationship that exists between cannabis use and depression is an extremely complex one. This study's main objective is to review previously conducted research regarding the association between cannabis use and depression in adolescents.

摘要

青春期是一个个体经历多种生理和心理变化的阶段,这些变化增加了他们受环境影响的易感性。接触大麻是一个可能危及他们健康的环境因素。各种研究一致认为,抑郁症的发作与大麻使用之间存在联系。大麻会影响青少年的大脑,使他们易患抑郁症。抑郁症是一种以多种可能对个体有害的方式表现出来的疾病。这个问题不仅局限于个体本身,也是一个社会问题。大麻使用与抑郁症之间的关系极其复杂。本研究的主要目的是回顾先前关于青少年大麻使用与抑郁症之间关联的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2640/9418628/61d822e9c56c/cureus-0014-00000027394-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2640/9418628/bea88598614e/cureus-0014-00000027394-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2640/9418628/66cdd47dc72f/cureus-0014-00000027394-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2640/9418628/61d822e9c56c/cureus-0014-00000027394-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2640/9418628/bea88598614e/cureus-0014-00000027394-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2640/9418628/66cdd47dc72f/cureus-0014-00000027394-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2640/9418628/61d822e9c56c/cureus-0014-00000027394-i03.jpg

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本文引用的文献

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Effects of Adolescent Cannabis Use on Motivation and Depression: A Systematic Review.青少年使用大麻对动机和抑郁的影响:一项系统综述。
Curr Addict Rep. 2019 Dec;6(4):532-546. doi: 10.1007/s40429-019-00274-y. Epub 2019 Aug 29.
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Pro-Inflammatory Cytokines: Potential Links between the Endocannabinoid System and the Kynurenine Pathway in Depression.促炎细胞因子:内源性大麻素系统与抑郁症中犬尿氨酸途径之间的潜在联系。
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Cannabis use and cannabis use disorder.大麻使用和大麻使用障碍。
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Cannabinoids and Cannabinoid Receptors: The Story so Far.大麻素与大麻素受体:迄今为止的故事。
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Cannabis use among U.S. adolescents in the era of marijuana legalization: a review of changing use patterns, comorbidity, and health correlates.大麻合法化时代美国青少年的大麻使用情况:使用模式变化、共病和健康相关性的综述。
Int Rev Psychiatry. 2020 May;32(3):221-234. doi: 10.1080/09540261.2020.1713056. Epub 2020 Feb 6.
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Relationship between cannabis use frequency and major depressive disorder in adolescents: Findings from the National Survey on Drug Use and Health 2012-2017.青少年大麻使用频率与重度抑郁症之间的关系:2012-2017 年全国毒品使用与健康调查结果。
Drug Alcohol Depend. 2020 Mar 1;208:107867. doi: 10.1016/j.drugalcdep.2020.107867. Epub 2020 Jan 16.
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News Feature: Cannabis and the adolescent brain.新闻特写:大麻与青少年大脑
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