Department of Mathematical Sciences, School of Social Sciences, University of Southampton, Southampton, Hampshire, United Kingdom.
Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
PLoS One. 2022 Sep 2;17(9):e0273285. doi: 10.1371/journal.pone.0273285. eCollection 2022.
Although COVID-19 vaccines hold the potential to dramatically alter the COVID-19 pandemic, vaccine hesitancy remains a serious threat to the management and control of COVID-19 infections. Vaccination of young adults plays a crucial role in achieving herd immunity. However, the determinants of COVID-19 vaccine acceptance among the youth in China have not been fully explored. Our study aims to investigate the direct and indirect effects of perceived health literacy on COVID-19 vaccine acceptance.
This survey was conducted among Chinese college students during September and October, 2020. COVID-19 vaccine acceptance was defined as the likelihood that participants would get a COVID-19 vaccine. A mediation analysis was employed to explore the direct and indirect effects of perceived health literacy on COVID-19 vaccine acceptance.
A total of 2,587 college students were included in our study. The results of the survey revealed that the majority (80.40%) of the participants expressed high COVID-19 vaccine acceptance. After controlling for demographic characteristics, the relationship between perceived health literacy and COVID-19 vaccine acceptance was mediated by positive attitudes toward general vaccination (std.β = 0.004, p = 0.037) and self-efficacy of COVID-19 vaccine (std.β = 0.053, p < 0.001).
The findings suggest that interventions targeting health literacy to promote COVID-19 vaccination coverage might consider placing greater emphasis on enhancing the positive attitude towards and self-efficacy of vaccines among youth.
尽管 COVID-19 疫苗具有显著改变 COVID-19 大流行的潜力，但疫苗犹豫仍然是 COVID-19 感染管理和控制的严重威胁。为年轻人接种疫苗对于实现群体免疫至关重要。然而，中国青年对 COVID-19 疫苗的接受程度的决定因素尚未得到充分探索。我们的研究旨在调查感知健康素养对 COVID-19 疫苗接种接受度的直接和间接影响。
本研究于 2020 年 9 月至 10 月期间在中国大学生中进行。COVID-19 疫苗接种接受度定义为参与者接种 COVID-19 疫苗的可能性。采用中介分析探讨感知健康素养对 COVID-19 疫苗接种接受度的直接和间接影响。
共有 2587 名大学生纳入本研究。调查结果显示，大多数（80.40%）参与者表示高度接受 COVID-19 疫苗。在控制人口统计学特征后，感知健康素养与 COVID-19 疫苗接种接受度之间的关系通过对一般接种的积极态度（std.β=0.004，p=0.037）和 COVID-19 疫苗的自我效能（std.β=0.053，p<0.001）得到中介。
研究结果表明，针对健康素养的干预措施来提高 COVID-19 疫苗接种覆盖率可能需要更加注重增强年轻人对疫苗的积极态度和自我效能。
