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欧洲特应性皮炎指南(EuroGuiDerm)- 第二部分:非系统性治疗和特殊特应性皮炎患者人群的治疗建议。

European guideline (EuroGuiDerm) on atopic eczema - part II: non-systemic treatments and treatment recommendations for special AE patient populations.

机构信息

Department of Dermatology and Allergy, LMU Munich, Munich, Germany.

Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Dermatology, Brussels, Belgium.

出版信息

J Eur Acad Dermatol Venereol. 2022 Nov;36(11):1904-1926. doi: 10.1111/jdv.18429. Epub 2022 Sep 3.

Abstract

The evidence- and consensus-based guideline on atopic eczema was developed in accordance with the EuroGuiDerm Guideline and Consensus Statement Development Manual. Four consensus conferences were held between December 2020 and July 2021. Twenty-nine experts (including clinicians and patient representatives) from 12 European countries participated. This second part of the guideline includes recommendations and detailed information on basic therapy with emollients and moisturizers, topical anti-inflammatory treatment, antimicrobial and antipruritic treatment and UV phototherapy. Furthermore, this part of the guideline covers techniques for avoiding provocation factors, as well as dietary interventions, immunotherapy, complementary medicine and educational interventions for patients with atopic eczema and deals with occupational and psychodermatological aspects of the disease. It also contains guidance on treatment for paediatric and adolescent patients and pregnant or breastfeeding women, as well as considerations for patients who want to have a child. A chapter on the patient perspective is also provided. The first part of the guideline, published separately, contains recommendations and guidance on systemic treatment with conventional immunosuppressive drugs, biologics and janus kinase (JAK) inhibitors, as well as information on the scope and purpose of the guideline, and a section on guideline methodology.

摘要

这份基于循证和共识的特应性皮炎指南是根据 EuroGuiDerm 指南和共识声明制定手册制定的。在 2020 年 12 月至 2021 年 7 月期间举行了四次共识会议。来自 12 个欧洲国家的 29 名专家(包括临床医生和患者代表)参加了会议。本指南的第二部分包括有关保湿剂和润肤剂基础治疗、局部抗炎治疗、抗菌和止痒治疗以及紫外线光疗的建议和详细信息。此外,本指南的这一部分还涵盖了避免诱发因素的技术,以及饮食干预、免疫疗法、补充医学和特应性皮炎患者的教育干预措施,涉及疾病的职业和精神皮肤病学方面。它还包含了针对儿科和青少年患者以及孕妇或哺乳期妇女的治疗指南,以及针对希望生育的患者的考虑因素。还提供了关于患者视角的一章。单独发布的指南的第一部分包含了关于传统免疫抑制剂、生物制剂和 JAK 抑制剂的全身治疗的建议和指导,以及指南的范围和目的信息,以及指南方法学部分。

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