Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Cancer Scan, 1-3-8, Nishigotanda, Shinagawa-Ku, Tokyo, 141-0031, Japan.
Int J Clin Oncol. 2022 Nov;27(11):1750-1757. doi: 10.1007/s10147-022-02240-7. Epub 2022 Sep 3.
In Japan, HPV vaccination rates has dramaticaly declined since 2013. Since mothers are the ones making the decision to vaccinate their daughters against HPV, we probed the mothers' intention to receive vaccinations for themselves and to vaccinate their daughters against HPV, and their reasoning.
An internet survey was conducted in March of 2021. Through the screening, 1576 participants were extracted from a survey panel and divided into 3 groups based on their daughter's birth fiscal year (Group 1: 1994 to 1999, Group 2: 2000 to 2003, Group3: 2004 to 2008). The chi-square test and residual analysis were used for the statistical analysis of comparison among the groups. Logistic regression analysis was used to identify independent variables with mothers intention to get their daughters vaccinated under specific situations.
The percentage of respondents without anxiety regarding their daughter's general vaccination was significantly higher in Group 1 (p < 0.05). In the mothers of daughters born in or after 2000 when vaccination rates declined (Groups 2 and 3), a situation in which 'The daughter's best friends were vaccinated before her' made the mothers think positively about HPV vaccination, and to the same degree as a situation in which 'You received a notice from your local government recommending vaccination' (Group 2: 41.6% (214/514) and 40.5% (208/514), Group 3: 48.5% (257/530) and 47.0% (249/530)).
If mothers who have had their daughters vaccinated were to recommend HPV vaccination to their close friends, 'the best friend effect' should promote others to be vaccinated.
在日本，自 2013 年以来，HPV 疫苗接种率大幅下降。由于母亲是决定为女儿接种 HPV 疫苗的人，因此我们探究了母亲为自己接种疫苗和为女儿接种 HPV 疫苗的意愿及其原因。
我们于 2021 年 3 月进行了一项互联网调查。通过筛选，从一个调查小组中提取了 1576 名参与者，并根据女儿的出生财政年度将其分为 3 组（第 1 组：1994 年至 1999 年，第 2 组：2000 年至 2003 年，第 3 组：2004 年至 2008 年）。使用卡方检验和残差分析对组间比较进行统计学分析。使用逻辑回归分析来确定在特定情况下母亲为女儿接种疫苗的意愿的独立变量。
在女儿常规疫苗接种方面无焦虑的受访者百分比在第 1 组中显著更高（p<0.05）。在疫苗接种率下降的 2000 年及以后出生的女儿的母亲中，当“女儿的最好朋友在她之前接种了疫苗”时，母亲会对 HPV 疫苗接种产生积极的想法，其程度与“您收到了当地政府推荐接种疫苗的通知”相同（第 2 组：41.6%（214/514）和 40.5%（208/514），第 3 组：48.5%（257/530）和 47.0%（249/530））。
如果已经为女儿接种疫苗的母亲向亲密朋友推荐 HPV 疫苗接种，那么“最好朋友效应”应该会促使其他人接种疫苗。
