Department of Agricultural, Food, and Nutritional Sciences, Division of Human Nutrition, University of Alberta, Edmonton, Alberta, Canada; Department of Nutrition, Nursing School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Department of Nutrition, Nursing School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Department of Psychiatry and Behavioral Sciences, Neuropsychiatry Program, University of Texas Health Science Center, Houston, Texas.
Nutrition. 2022 Nov-Dec;103-104:111803. doi: 10.1016/j.nut.2022.111803. Epub 2022 Jul 25.
Food components with thermogenic properties are promising antiobesity agents. Ginger (Zingiber officinale Rosc.) bioactive compounds have a capsaicin-like vanillyl portion, which has been attributed to thermogenic effect in previous experimental studies. However, studies conducted in humans have evaluated only the acute thermogenic effect of ginger, and demonstrated contradictory results. We evaluated the effect of long-term consumption of dry ginger extract on the resting energy expenditure (REE) of female adults with high body adiposity.
This is a secondary analysis of a randomized, double-blind, placebo-controlled clinical trial (NCT02570633). Participants age 18 to 60 y were randomly assigned into two groups: Intervention (600 mg of ginger extract daily) and placebo (cellulose). The intervention lasted 3 mo. Anthropometric measurements, blood pressure, and REE were assessed at each visit.
A total of 66 female participants with high body adiposity were included in the analysis (mean age: 29 y [range, 20-55 y]; body mass index: 23.3 ± 2.7), with 30 participants in the ginger group and 36 in the placebo group. There were no significant differences in baseline characteristics between the groups. No differences were observed for group × time interaction on REE. Body composition and blood pressure followed the same pattern (all P > 0.05).
Ginger extract consumption for 3 mo did not change the REE, anthropometric, and clinical data of female adults with excess adiposity.
具有产热特性的食物成分是有前途的抗肥胖剂。生姜（Zingiber officinale Rosc.）生物活性化合物具有类似于辣椒素的香草基部分，这在以前的实验研究中归因于产热作用。然而，在人类中进行的研究仅评估了生姜的急性产热作用，并且得出了相互矛盾的结果。我们评估了长期食用干姜提取物对体脂过高的成年女性静息能量消耗（REE）的影响。
这是一项随机、双盲、安慰剂对照临床试验（NCT02570633）的二次分析。年龄在 18 至 60 岁的参与者被随机分为两组：干预组（每天 600 毫克生姜提取物）和安慰剂组（纤维素）。干预持续 3 个月。每次就诊时评估体重指数、血压和 REE。
共有 66 名体脂过高的女性参与者纳入分析（平均年龄：29 岁[范围，20-55 岁]；体重指数：23.3 ± 2.7），其中 30 名参与者在生姜组，36 名参与者在安慰剂组。两组间基线特征无显著差异。REE 无组间时间交互作用差异。体成分和血压遵循相同模式（均 P > 0.05）。
干姜提取物连续摄入 3 个月不会改变超重成年女性的 REE、人体成分和临床数据。
