Pustake Manas, Ganiyani Mohammad Arfat, Shah Dhwani, Dhondge Vijay, Deshmukh Krishna
Internal Medicine, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, IND.
Global Clinical Scholars Research Training, Harvard Medical School, Boston, USA.
Cureus. 2022 Aug 1;14(8):e27588. doi: 10.7759/cureus.27588. eCollection 2022 Aug.
An 86-year-old male presented with fever and joint pain for seven days. Clinical features were suggestive of chikungunya fever, but reverse transcription-polymerase chain reaction (RT-PCR) was negative. After ruling out the differentials, the patient was clinically diagnosed with chikungunya fever. Chikungunya IgG antibody was positive two months after the onset of symptoms. He had a history of asymptomatic coronavirus disease (COVID-19) infection two months ago. About 20 days after his first symptom, he developed bipedal edema, refractory to diuretics. All other causes of pedal edema, including heart failure, renal failure, and liver failure, were ruled out. The bipedal edema was managed conservatively with compression bandages. Only a few case reports and studies on limb edema as a symptom post chikungunya fever have been published up to this point. Furthermore, it is difficult to say whether his COVID-19 infection is linked to the edema.
一名86岁男性出现发热和关节疼痛7天。临床特征提示为基孔肯雅热,但逆转录聚合酶链反应(RT-PCR)结果为阴性。在排除各种鉴别诊断后,该患者被临床诊断为基孔肯雅热。症状出现两个月后,基孔肯雅IgG抗体呈阳性。他两个月前有过无症状冠状病毒病(COVID-19)感染史。在出现首个症状约20天后,他出现双下肢水肿,利尿剂治疗无效。排除了包括心力衰竭、肾衰竭和肝衰竭在内的所有导致足部水肿的其他原因。双下肢水肿采用压迫绷带进行保守治疗。截至目前,仅有少数关于基孔肯雅热后肢体水肿症状的病例报告和研究发表。此外,很难说他的COVID-19感染是否与水肿有关。