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肢体继发性淋巴水肿与基孔肯雅热

Secondary lymphedema of limbs and chikungunya fever.

作者信息

Marques Marcos Arêas, Milhomens Ana Letícia de Matos, Vieira Juliana de Miranda, Cardoso Fabricius Rocha, Guedes Henrique Jorge

机构信息

Universidade do Estado do Rio de Janeiro - UERJ, Rio de Janeiro, RJ, Brasil.

Universidade Federal do Estado do Rio de Janeiro - UNIRIO, Rio de Janeiro, RJ, Brasil.

出版信息

J Vasc Bras. 2019 May 22;18:e20190015. doi: 10.1590/1677-5449.190015.

Abstract

Certain systemic viral infections can be related to development of vascular complications, such as deep venous thrombosis and lymphedema of lower and upper limbs. These links have been well-established in patients with human immunodeficiency virus (HIV), hepatitis C, or influenza. Recently introduced into the American continent (2013), chikungunya virus is an arbovirus transmitted by mosquitoes of the genus and is the etiologic agent of chikungunya fever (CF), but its relationship to these vascular complications has not yet been consolidated. However, the CF outbreak that occurred during 2015 and 2016 resulted in the first cases described in the medical literature of acute and chronic vascular complications secondary to infection by this arbovirus. In this report, we describe the case of a patient who developed lymphedema of upper and lower limbs after an episode of CF.

摘要

某些全身性病毒感染可能与血管并发症的发生有关,如下肢和上肢的深静脉血栓形成和淋巴水肿。这些关联在人类免疫缺陷病毒(HIV)、丙型肝炎或流感患者中已得到充分证实。基孔肯雅病毒于2013年新近传入美洲大陆,是一种由该属蚊子传播的虫媒病毒,是基孔肯雅热(CF)的病原体,但其与这些血管并发症的关系尚未得到证实。然而,2015年至2016年期间发生的CF疫情导致了医学文献中首次描述的由这种虫媒病毒感染继发的急性和慢性血管并发症病例。在本报告中,我们描述了一例CF发作后出现上下肢淋巴水肿的患者病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57b5/6634949/da43652ec63c/jvb-18-e20190015-g01-en.jpg

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