Kaysner C A, Abeyta C, Wekell M M, DePaola A, Stott R F, Leitch J M
Appl Environ Microbiol. 1987 Jun;53(6):1349-51. doi: 10.1128/aem.53.6.1349-1351.1987.
Vibrio vulnificus was isolated from United States West Coast estuaries at a low frequency (5.9%) from 529 samples of water, shellfish, and sediment. Four strains tested with iron-treated mice had 50% lethal dose values ranging from 7.6 to 360 CFU, compared with a 50% lethal dose of 4.9 CFU for a clinical isolate that caused the death of a septicemic patient. The presence of this pathogen may be a hazard to users of marine beaches and consumers of raw shellfish on the West Coast, especially to persons most susceptible to V. vulnificus septicemia. Species-specific antiflagellar serum and a gene probe for cytotoxin-hemolysin production were useful for screening these environmental isolates.
创伤弧菌是从美国西海岸河口的529份水、贝类和沉积物样本中以低频率（5.9%）分离出来的。用铁处理过的小鼠对4株菌株进行测试，其半数致死剂量值在7.6至360 CFU之间，而导致一名败血症患者死亡的临床分离株的半数致死剂量为4.9 CFU。这种病原体的存在可能对西海岸海滩使用者和生贝类消费者构成危害，尤其是对最易感染创伤弧菌败血症的人群。种特异性抗鞭毛血清和用于检测细胞毒素-溶血素产生的基因探针可用于筛选这些环境分离株。
