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新型扫频源光相干生物测量仪在光学生物测量中的可重复性和可比性。

Repeatability and comparability of a new swept-source optical coherence tomographer in optical biometry.

机构信息

Servicio de Oftalmología, Hospital General Universitario de Elche, Alicante, Spain; Programa de Doctorado en Salud Pública, Ciencias Médicas y Quirúrgicas, Universidad Miguel Hernández de Elche, Alicante, Spain.

Servicio de Oftalmología, Hospital General Universitario de Elche, Alicante, Spain.

出版信息

Arch Soc Esp Oftalmol (Engl Ed). 2022 Dec;97(12):670-675. doi: 10.1016/j.oftale.2022.04.003. Epub 2022 Sep 6.

DOI:10.1016/j.oftale.2022.04.003
PMID:36068133
Abstract

PURPOSE

To evaluate the reproducibility in the measurement of ocular biometric parameters using a new swept-source optical coherence tomographer and its comparability with an optical low coherence reflectometry biometer.

DESIGN

An observational, descriptive, cross-sectional study.

METHODS

45 right eyes of 45 patients diagnosed with cataract were included. Three successive biometric measurements with Anterion and one with Lenstar LS900 were performed on each patient. The following variables were collected: axial length (AXL), anterior chamber depth (ACD), flat K (K1), steep K (K2), central corneal thickness (CCT), lens thickness (LT) and white-to-white distance (WTW). The intrasubject standard deviation (S) and the coefficient of Pearson "R" were calculated in order to assess the repeatability. The intraclass correlation coefficient (ICC) and the concordance correlation coefficient (CCC) were obtained to evaluate the comparability between devices. A Bland-Altman plot was performed for each variable.

RESULTS

The coefficient of Pearson was excellent and statistically significant in the evaluation of the repeatability in all the variables. The highest values were 0.987 (AXL), 0.983 (CCT) and 0.942 (ACD). There were no statically significant differences between repeated measurements with Anterion in all the parameters. The ICC and CCC were excellent in the evaluation of AXL, CCT and ACD, and were also good in regard to K1, K2, LT and WTW.

CONCLUSIONS

Performing biometry with the SS-OCT Anterion is a reliable and reproducible procedure, and it is comparable with the Lenstar LS900.

摘要

目的

评估使用新型扫频源光相干断层扫描仪测量眼生物测量参数的可重复性及其与光低相干反射生物测量仪的可比性。

设计

观察性、描述性、横断面研究。

方法

纳入 45 例经临床诊断为白内障的患者的 45 只右眼。对每位患者连续进行 3 次 Anterion 生物测量和 1 次 Lenstar LS900 生物测量。收集以下变量:眼轴长度(AXL)、前房深度(ACD)、平 K 值(K1)、陡 K 值(K2)、中央角膜厚度(CCT)、晶状体厚度(LT)和白到白距离(WTW)。计算各变量的组内标准差(S)和皮尔逊“R”系数,以评估重复性。获得组内相关系数(ICC)和一致性相关系数(CCC),以评估两种设备的可比性。对每个变量进行 Bland-Altman 图分析。

结果

在评估所有变量的重复性时,皮尔逊系数均为极好且具有统计学意义。最高值为 0.987(AXL)、0.983(CCT)和 0.942(ACD)。在所有参数中,Anterion 重复测量均无统计学差异。在评估 AXL、CCT 和 ACD 时,ICC 和 CCC 均为极好,在评估 K1、K2、LT 和 WTW 时也为良好。

结论

使用 SS-OCT Anterion 进行生物测量是一种可靠且可重复的方法,与 Lenstar LS900 具有可比性。

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