Romero Daniel, Monera Carlos E, Cooke David, Alio Jorge L, Tarazona Claudia, Martínez-Toldos Jose Juan
Department of Ophthalmology, General University Hospital of Elche, Elche Foundation for the Promotion of Health and Biomedical Research in the Valencian Region (FISABIO), Valencia, Spain.
Great Lakes Eye Care, St. Joseph, MI, USA.
Clin Ophthalmol. 2025 Jun 26;19:2021-2028. doi: 10.2147/OPTH.S515167. eCollection 2025.
To evaluate the comparability of biometric measurements obtained using the swept-source optical coherence tomography (SS-OCT) biometer (Anterion) and the optical low-coherence reflectometry (OLCR) biometer (Lenstar LS900).
This observational study included 150 cataract patients undergoing preoperative biometry at the General University Hospital of Elche. Measurements from the Anterion and Lenstar LS900 were compared for axial length (AL), mean keratometry (Km), anterior chamber depth (ACD), lens thickness (LT), and central corneal thickness (CCT). Bland-Altman plots and statistical analyses were conducted to assess differences and correlations.
The mean AL measurements showed no significant difference between the two devices (mean difference -0.004 ± 0.053 mm, P = 0.420). ACD and LT measurements displayed statistically significant differences, with Anterion showing greater mean values (ACD difference: 0.054 ± 0.037 mm, P < 0.001; LT difference: 0.107 ± 0.079 mm, P < 0.001). Mean keratometry was significantly flatter by 0.074 ± 0.259D (P = 0.001) in Anterion compared to Lenstar, primarily due to differences in steep keratometry. No correlation was found between keratometry differences and corneal asphericity. Estimated intraocular lens (IOL) power for emmetropia was significantly higher using Anterion by 0.146 ± 0.398D (P < 0.001), necessitating an A-constant adjustment of approximately 0.16 to equal mean IOL power in both devices.
a good correlation was found between both biometers. However, due to the differences found between biometric measurements between devices, these two biometers should not be considered interchangeable and clinicians should adjust IOL constants accordingly. Future studies will be necessary to determine whether one biometer is superior to the other in terms of refractive outcome predictability.
评估使用扫频光学相干断层扫描（SS-OCT）生物测量仪（Anterion）和光学低相干反射测量法（OLCR）生物测量仪（Lenstar LS900）获得的生物测量数据的可比性。
这项观察性研究纳入了150例在埃尔切综合大学医院接受术前生物测量的白内障患者。比较了Anterion和Lenstar LS900在眼轴长度（AL）、平均角膜曲率（Km）、前房深度（ACD）、晶状体厚度（LT）和中央角膜厚度（CCT）方面的测量结果。进行了Bland-Altman图分析和统计分析以评估差异和相关性。
两种设备的平均AL测量结果无显著差异（平均差值-0.004±0.053mm，P = 0.420）。ACD和LT测量结果显示出统计学上的显著差异，Anterion的平均值更高（ACD差值：0.054±0.037mm，P < 0.001；LT差值：0.107±0.079mm，P < 0.001）。与Lenstar相比，Anterion的平均角膜曲率明显更平坦，差值为0.074±0.259D（P = 0.001），这主要是由于陡峭角膜曲率的差异。角膜曲率差异与角膜非球面性之间未发现相关性。使用Anterion时，正视眼的预估人工晶状体（IOL）度数显著更高，差值为0.146±0.398D（P < 0.001），需要将A常数调整约0.16才能使两种设备的平均IOL度数相等。
两种生物测量仪之间存在良好的相关性。然而，由于两种设备之间生物测量数据存在差异，这两种生物测量仪不应被视为可互换的，临床医生应相应地调整IOL常数。未来有必要进行研究以确定在屈光结果可预测性方面一种生物测量仪是否优于另一种。
