全自动扫频源光学相干断层扫描生物测量仪的可重复性及其与低相干反射测量生物测量仪的一致性。
Repeatability of a fully automated swept-source optical coherence tomography biometer and agreement with a low coherence reflectometry biometer.
作者信息
Domínguez-Vicent Alberto, Venkataraman Abinaya Priya, Dalin Amanda, Brautaset Rune, Montés-Micó Robert
机构信息
Division of Eye and Vision, Department of Clinical Neuroscience, Karolinska Institute, 171 77, Stockholm, Sweden.
Optics and Optometry and Vision Sciences Department, University of Valencia, Valencia, Spain.
出版信息
Eye Vis (Lond). 2023 Jun 2;10(1):24. doi: 10.1186/s40662-023-00343-4.
BACKGROUND
To evaluate the repeatability of a fully automated swept-source optical coherence tomography (SS-OCT) and its agreement with an optical low coherence reflectometry (OLCR) for several biometric parameters.
METHODS
In this study, 74 eyes of 74 patients were measured using the Eyestar 900 SS-OCT and Lenstar LS 900 OLCR. Flat keratometry (K1) and steep keratometry (K2), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) were measured three times with each device. The repeatability was analyzed with the intrasubject standard deviation, coefficient of variability (CoV), and coefficient of repeatability (CoR) for each instrument. The agreement between the instruments was evaluated with Bland-Altman analysis.
RESULTS
K1, K2 and CCT CoV values were < 0.2%, < 0.4% and < 0.55%, respectively. Higher CoV values were found for ACD and LT ranging from 0.56% to 1.74%. The lowest CoV values were found for the AL measurements (0.03% and 0.06% for the Eyestar 900 and the Lenstar LS 900, respectively). AL measurements provided the highest repeatability, measured with both CoV and CoR values, and the CCT was the parameter with the lowest repeatability. The CCT and LT measurements were statistically significant between the two biometers (P < 0.001). The interval of the limits of agreement was < 0.6 D for K1 and K2, 15.78 µm for CCT, 0.21 mm for ACD, 0.34 mm for LT, and 0.08 mm for AL.
CONCLUSIONS
Both biometers provide repeatable measurements for the different parameters analyzed and can be used interchangeably.
背景
评估全自动化扫频光学相干断层扫描（SS-OCT）的可重复性及其与光学低相干反射测量法（OLCR）在多个生物测量参数方面的一致性。
方法
在本研究中，使用Eyestar 900 SS-OCT和Lenstar LS 900 OLCR对74例患者的74只眼睛进行测量。用每种设备对平坦角膜曲率（K1）、陡峭角膜曲率（K2）、中央角膜厚度（CCT）、前房深度（ACD）、晶状体厚度（LT）和眼轴长度（AL）进行三次测量。用受试者内标准差、变异系数（CoV）和重复性系数（CoR）分析每种仪器的可重复性。用Bland-Altman分析评估仪器之间的一致性。
结果
K1、K2和CCT的CoV值分别<0.2%、<0.4%和<0.55%。ACD和LT的CoV值较高，范围为0.56%至1.74%。AL测量的CoV值最低（Eyestar 900和Lenstar LS 900分别为0.03%和0.06%）。用CoV和CoR值衡量，AL测量的重复性最高，而CCT是重复性最低的参数。两种生物测量仪之间CCT和LT测量结果具有统计学意义（P<0.001）。一致性界限的区间为：K1和K2<0.6 D，CCT为15.78 µm，ACD为0.21 mm，LT为0.34 mm，AL为0.08 mm。
结论
两种生物测量仪对所分析的不同参数均能提供可重复的测量结果，且可互换使用。
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