Prommaban Adchara, Kheawfu Kantaporn, Chittasupho Chuda, Sirilun Sasithorn, Hemsuwimon Kirachuda, Chaiyana Wantida
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Research Center of Pharmaceutical Nanotechnology, Chiang Mai University, Chiang Mai 50200, Thailand.
Evid Based Complement Alternat Med. 2022 Aug 29;2022:5761764. doi: 10.1155/2022/5761764. eCollection 2022.
L. (tobacco) is an important and valuable crop for the cigarette industry. However, cigarette cessation has been encouraged worldwide. Therefore, this study aimed to investigate the potential of leaf extract use in other industries besides cigarette production, especially cosmeceutical industries, which are of interest for increasing the value and widening the applications of . The leaves of var. Virginia and Turkish were extracted by maceration using 95% v/v ethanol or petroleum ether. The extracts were evaluated for their phytochemical compositions, antioxidant capacity, and anti-aging, antimelanogenic, and antimicrobial activities. The phytochemical screening of the extracts revealed terpenoids, steroids, alkaloids, tannins, and carbohydrates in all of the leaf extracts. The total phenolic content was detected to be the highest in the ethanolic extract of Virginia tobacco leaf, which had the most significantly potent antioxidant and antihyaluronidase activity ( < 0.05). On the contrary, the extracts from the Turkish variety demonstrated the most powerful antimicrobial activity against . Thus, ethanolic extracts of var. Virginia are suggested as good natural anti-aging ingredients with potent antioxidant and antihyaluronidase effects, whereas the leaf of var. Turkish is suggested as a good source of natural antimicrobial components, particularly for inhibition. In summary, in addition to the cigarette industry, leaf could be a source of pharmaceutical and cosmeceutical compounds, particularly natural anti-aging and antimicrobial ingredients.
烟草是卷烟行业重要且有价值的作物。然而，全球都在鼓励戒烟。因此，本研究旨在探究烟草叶提取物除用于卷烟生产外，在其他行业，特别是药妆行业的潜在用途，药妆行业对于提高烟草的价值和拓宽其应用领域具有重要意义。采用95%（v/v）乙醇或石油醚浸渍法提取弗吉尼亚烟草变种和土耳其烟草的叶片。对提取物的植物化学成分、抗氧化能力以及抗老化、抗黑色素生成和抗菌活性进行了评估。提取物的植物化学筛选显示，所有烟草叶提取物中均含有萜类、甾体、生物碱、单宁和碳水化合物。检测发现弗吉尼亚烟草叶乙醇提取物中的总酚含量最高，其具有最显著的抗氧化和抗透明质酸酶活性（P<0.05）。相反，土耳其烟草变种的提取物对[具体微生物名称未给出]表现出最强的抗菌活性。因此，建议弗吉尼亚烟草变种的乙醇提取物作为具有强大抗氧化和抗透明质酸酶作用的优质天然抗老化成分，而土耳其烟草变种的叶片则被认为是天然抗菌成分的良好来源，特别是对[具体微生物名称未给出]有抑制作用。总之，除了卷烟行业，烟草叶还可能是药物和药妆化合物的来源，特别是天然抗老化和抗菌成分。
