Sun Weiwei, Chen Jungang, Yan Li, Lin Jinzhao, Pang Yu, Zhang Guo
Chongqing University of Posts and Telecommunication, Chongqing, China.
School of Medical Information and Engineering, Southwest Medical University, Luzhou, China.
Front Physiol. 2022 Aug 22;13:981463. doi: 10.3389/fphys.2022.981463. eCollection 2022.
Owing to its significant contagion and mutation, the new crown pneumonia epidemic has caused more than 520 million infections worldwide and has brought irreversible effects on the society. Computed tomography (CT) images can clearly demonstrate lung lesions of patients. This study used deep learning techniques to assist doctors in the screening and quantitative analysis of this disease. Consequently, this study will help to improve the diagnostic efficiency and reduce the risk of infection. In this study, we propose a new method to improve U-Net for lesion segmentation in the chest CT images of COVID-19 patients. 750 annotated chest CT images of 150 patients diagnosed with COVID-19 were selected to classify, identify, and segment the background area, lung area, ground glass opacity, and lung parenchyma. First, to address the problem of a loss of lesion detail during down sampling, we replaced part of the convolution operation with atrous convolution in the encoder structure of the segmentation network and employed convolutional block attention module (CBAM) to enhance the weighting of important feature information. Second, the Swin Transformer structure is introduced in the last layer of the encoder to reduce the number of parameters and improve network performance. We used the CC-CCII lesion segmentation dataset for training and validation of the model effectiveness. The results of ablation experiments demonstrate that this method achieved significant performance gain, in which the mean pixel accuracy is 87.62%, mean intersection over union is 80.6%, and dice similarity coefficient is 88.27%. Further, we verified that this model achieved superior performance in comparison to other models. Thus, the method proposed herein can better assist doctors in evaluating and analyzing the condition of COVID-19 patients.
由于新冠疫情具有显著的传染性和变异性,已在全球范围内造成超过5.2亿人感染,并给社会带来了不可逆转的影响。计算机断层扫描(CT)图像能够清晰地显示患者的肺部病变。本研究运用深度学习技术辅助医生对该疾病进行筛查和定量分析。因此,本研究将有助于提高诊断效率并降低感染风险。在本研究中,我们提出了一种改进U-Net的新方法,用于分割新冠肺炎患者胸部CT图像中的病变。我们选取了150例确诊为新冠肺炎患者的750张标注胸部CT图像,对背景区域、肺区域、磨玻璃影和肺实质进行分类、识别和分割。首先,为了解决下采样过程中病变细节丢失的问题,我们在分割网络的编码器结构中用空洞卷积替换了部分卷积操作,并采用卷积块注意力模块(CBAM)来增强重要特征信息的权重。其次,在编码器的最后一层引入Swin Transformer结构,以减少参数数量并提高网络性能。我们使用CC-CCII病变分割数据集对模型有效性进行训练和验证。消融实验结果表明,该方法取得了显著的性能提升,其中平均像素准确率为87.62%,平均交并比为80.6%,骰子相似系数为88.27%。此外,我们验证了该模型与其他模型相比具有更优的性能。因此,本文提出的方法能够更好地辅助医生评估和分析新冠肺炎患者的病情。