Biomedical Group (BIO277), University of Granada, Granada, Spain.
Department of Physiotherapy, Faculty of Health Sciences, University of Granada, Granada, Spain.
Sci Rep. 2022 Sep 8;12(1):15217. doi: 10.1038/s41598-022-18706-7.
Physical exercise is known to be beneficial for breast cancer survivors (BCS). However, avoiding nonfunctional overreaching is crucial in this population, as they are in physiological dysregulation. These factors could decrease their exercise capacity or facilitate nonfunctional overreaching, which can increase their risk of additional morbidities and even all-cause mortality. The focus of this study is to evaluate the reliability and validity of the ATOPE+ mHealth system to estimate autonomic balance and specific wellness parameters associated with BCS' perceived load, thereby informing nonlinear prescriptions in individualized physical exercise programs for BCS.Twenty-two BCS were included in the reliability and validity analysis. Measures were taken for four days, including morning autonomic balance by heart rate variability, self-reported perception of recovery from exercise, sleep satisfaction, emotional distress and fatigue after exertion. Measures were taken utilizing the ATOPE+ mHealth system application. The results of these measures were compared with criterion instruments to assess validity.The reliability results indicated that the intraclass correlation coefficient (ICC) showed an excellent correlation for recovery (0.93; 95% CI 0.85-0.96) and distress (0.94, 95% CI 0.89-0.97) as well as good correlation for the natural logarithm of the mean square root differences of the standard deviation (LnRMSSD) (0.87; 95% CI 0.74-0.94). Sleep satisfaction also showed an excellent correlation with a weighted kappa of 0.83. The validity results showed no significant differences, except for fatigue. ATOPE+ is reliable and valid for remotely assessing autonomic balance, perception of recovery, sleep satisfaction and emotional distress in BCS; however, it is not for fatigue. This highlights that ATOPE+ could be an easy and efficient system used to assess readiness in BCS, and could help to improve their health by supporting the prescription of optimal and safe physical exercise. Trial registration NCT03787966 ClinicalTrials.gov, December 2019 [ATOPE project]. https://clinicaltrials.gov/ct2/show/NCT03787966 .
身体活动对乳腺癌幸存者（BCS）有益。然而，避免非功能性过度训练对这一人群至关重要，因为他们的生理机能失调。这些因素可能会降低他们的运动能力或促进非功能性过度训练，从而增加他们的额外发病风险，甚至全因死亡率。本研究的重点是评估 ATOPE+移动健康系统评估自主平衡和与 BCS 感知负荷相关的特定健康参数的可靠性和有效性，从而为 BCS 的个体化体育锻炼计划提供非线性处方信息。22 名 BCS 被纳入可靠性和有效性分析。连续四天进行测量，包括心率变异性的早晨自主平衡、自我报告的运动恢复感知、睡眠满意度、情绪困扰和用力后的疲劳。使用 ATOPE+移动健康系统应用程序进行测量。将这些测量结果与标准仪器进行比较，以评估有效性。可靠性结果表明，内类相关系数（ICC）显示恢复（0.93；95%置信区间 0.85-0.96）和痛苦（0.94，95%置信区间 0.89-0.97）的相关性极好，以及标准偏差均方根差的自然对数（LnRMSSD）（0.87；95%置信区间 0.74-0.94）的相关性良好。睡眠满意度的相关性也极好，加权kappa 值为 0.83。有效性结果除疲劳外，均无显著差异。ATOPE+可远程评估 BCS 的自主平衡、恢复感知、睡眠满意度和情绪困扰，具有可靠性和有效性；然而，它不能评估疲劳。这突出表明，ATOPE+可以成为一种简单有效的系统，用于评估 BCS 的准备情况，并通过支持最佳和安全的体育锻炼处方，帮助改善他们的健康状况。试验注册 NCT03787966 ClinicalTrials.gov，2019 年 12 月[ATOPE 项目]。https://clinicaltrials.gov/ct2/show/NCT03787966。
