Metabolism and Investigation Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Cordoba, Spain.
Ciencias De La Actividad Física y El Deporte, Escuela Universitaria de Osuna (Centro Adscrito a la Universidad de Sevilla), 41640 Osuna, Spain.
Int J Environ Res Public Health. 2022 Aug 24;19(17):10510. doi: 10.3390/ijerph191710510.
The main purpose of this study was to review the evidence about the effectiveness of exercise in patients with overweight or obesity suffering from knee osteoarthritis.
Randomized clinical trials (RCTs) published between January 2002 and May 2022 were included.
A total of 64 articles were identified, of which six met the criteria for meta-analysis. The pain scale score was higher in the control group (mean difference 0.95; confidence interval 0.42-1.47; < 0.001; I = 44%). The physical function scale (lower scores indicate lower levels of symptoms or physical disability) presented a higher score in the control group (mean difference 3.74; confidence interval 0.85-6.53; < 0.05; I = 56%). Moreover, the intervention group achieved a greater distance (meters) walking in a 6 min interval (mean difference 38.18; confidence interval 20.01-56.35; < 0.001; I = 0%).
Exercise interventions seem effective in improving quality of life in people with overweight or obesity suffering from knee osteoarthritis, reducing pain and improving physical function.
本研究的主要目的是回顾关于超重或肥胖的膝骨关节炎患者进行运动的有效性的证据。
纳入了 2002 年 1 月至 2022 年 5 月期间发表的随机临床试验（RCT）。
共确定了 64 篇文章，其中 6 篇符合荟萃分析的标准。对照组的疼痛量表评分较高（平均差异 0.95；置信区间 0.42-1.47；<0.001；I = 44%）。对照组的身体功能量表（得分越低表示症状或身体残疾程度越低）评分较高（平均差异 3.74；置信区间 0.85-6.53；<0.05；I = 56%）。此外，干预组在 6 分钟间隔内行走的距离（米）更长（平均差异 38.18；置信区间 20.01-56.35；<0.001；I = 0%）。
运动干预似乎可有效改善超重或肥胖的膝骨关节炎患者的生活质量，减轻疼痛并改善身体功能。
