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复方聚乙二醇电解质散对肠镜检查前肠道准备质量的影响

Effect of Compound Polyethylene Glycol Electrolyte Powder on the Quality of Gastrobowel Preparation before Enteroscopy Intervention.

作者信息

Yuan Yongxin, Li Yuqin, Zhang Yafeng, Jiang Jing, He Yi, Liao Yimei, Yao Wenchun

机构信息

Department of Anorectal, Suining Central Hospital, Suining, Sichuan 629000, China.

Department of Nuclear Medicine, Suining Central Hospital, Suining, Sichuan 629000, China.

出版信息

Emerg Med Int. 2022 Aug 31;2022:9895499. doi: 10.1155/2022/9895499. eCollection 2022.

DOI:10.1155/2022/9895499
PMID:36090542
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9452999/
Abstract

OBJECTIVE

To study the effect of compound polyethylene glycol electrolyte powder (PGEP) on the quality of gastrobowel preparation before enteroscopy intervention.

METHODS

From March 2021 to January 2022, among the patients who needed enteroscopy in our hospital, 280 patients who volunteered for this study were randomly selected as the research objects. All the subjects were randomly divided into the control group (140 cases) and the observation group (140 cases). Both groups received routine treatment before enteroscopy intervention. On this basis, patients in the control group were given 9 g of senna every day before operation, and 250 ml of 20% mannitol and 2500 ml of water were taken orally from 9:00 am to 11:00 am on the day of examination. Patients in the observation group took PGEP orally from 9:00 am to 11:00 am. The effective rate of bowel cleaning, the frequency of defecation and duration of diarrhea, the levels of blood electrolyte indexes such as Na, K, and Cl before and after the intervention, and the incidence of adverse reactions were compared between the two groups.

RESULTS

The effective rate of bowel cleaning in the observation group was significantly higher than that in the control group ( < 0.05). The frequency of defecation and duration of diarrhea in the observation group were significantly lower than those in the control group ( < 0.05). Compared with the control group, the levels of blood electrolyte indexes in the observation group after the intervention were not statistically significant ( > 0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group ( < 0.05).

CONCLUSION

Using PGEP for gastrobowel preparation before enteroscopy intervention can achieve high bowel cleaning efficiency, short bowel preparation time, and low incidence of adverse reactions, which does not affect the water-electrolyte balance of patients, and the psychological state of patients before enteroscopy intervention is more stable. This program is worthy of clinical promotion.

摘要

目的

研究复方聚乙二醇电解质散(PGEP)对肠镜检查前肠道准备质量的影响。

方法

选取2021年3月至2022年1月我院需行肠镜检查的患者,随机抽取280例自愿参与本研究的患者作为研究对象。将所有受试者随机分为对照组(140例)和观察组(140例)。两组在肠镜检查前均接受常规治疗。在此基础上,对照组患者术前每天服用9 g番泻叶,检查当天上午9:00至11:00口服250 ml 20%甘露醇及2500 ml水。观察组患者于上午9:00至11:00口服PGEP。比较两组肠道清洁有效率、排便次数及腹泻持续时间、干预前后血电解质指标Na、K、Cl水平及不良反应发生率。

结果

观察组肠道清洁有效率显著高于对照组(<0.05);观察组排便次数及腹泻持续时间显著低于对照组(<0.05)。与对照组比较,观察组干预后血电解质指标水平差异无统计学意义(>0.05)。观察组不良反应发生率显著低于对照组(<0.05)。

结论

肠镜检查前采用PGEP进行肠道准备,肠道清洁效率高,肠道准备时间短且不良反应发生率低,不影响患者水电解质平衡,患者肠镜检查前心理状态更稳定,该方案值得临床推广。

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[Influencing factors for the quality of bowel preparation with polyethylene glycol electrolyte powder combined with diet control before colonoscopy in children].[儿童结肠镜检查前聚乙二醇电解质散联合饮食控制肠道准备质量的影响因素]
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Nagoya J Med Sci. 2021 Nov;83(4):787-799. doi: 10.18999/nagjms.83.4.787.
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