Serotoninergic neurons: long-lasting activation by a possible antidepressant dihydroergosine.
作者信息
Pericić D, Manev H
出版信息
Eur J Pharmacol. 1987 May 7;137(1):123-5. doi: 10.1016/0014-2999(87)90190-7.
PMID:3609131
Abstract
The duration of the stimulating effect of one single i.p. injection of a possible antidepressant dihydroergosine (50 mg/kg) on the 5-HT syndrome was studied in rats. Dihydroergosine produced a very pronounced stimulation of the 5-HT syndrome which was still present after 1-144 h (6 days). The results suggest that dihydroergosine produces a long-lasting stimulation of serotoninergic neurons.
摘要
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