Department of Preventive Medicine, School of Public Health, Wuhan University, Wuhan, China.
Wuhan Prevention and Treatment Center for Occupational Diseases, Wuhan, China.
Front Public Health. 2022 Aug 25;10:990547. doi: 10.3389/fpubh.2022.990547. eCollection 2022.
Welding fumes are a risk factor for welder pneumoconiosis. However, there is a lack of population information on the occurrence of welding fume-induced lung cancer, and little is known about the welding fume pathogenesis.
Welding fume and metal ion concentrations were assessed in a vehicle factory in Wuhan. A Cox regression model estimated lung-related disease risk in workers by independent and combined factors.
Workers' exposures were divided into four grades; the highest exposure was among the welders in the maintenance workshop, the highest Mn and Fe exposure was 4 grades, and the highest Cr exposure was 3 grades. Subgroup analysis found that the risk of lung-related disease was 2.17 < in welders compared with non-welders, and the risk of pulmonary disease in male welders was 2.24 < compared to non-welders. Smoking welders had a 2.44 < higher incidence of lung-related diseases than non-welders. Total years of work as an independent protective factor for lung-related disease risk was 0.72 < . As an independent risk factor, high-high and high-low exposure had a 5.39 < and 2.17 < higher risk for lung-related diseases, respectively.
High welding fume exposure is a significant risk factor for lung-related disease in workers.
焊接烟尘是焊工尘肺的危险因素。然而，人群中关于焊接烟尘引起肺癌的发生情况的信息较少，对焊接烟尘发病机制也知之甚少。
在武汉的一家汽车厂评估了焊接烟尘和金属离子浓度。Cox 回归模型通过独立和组合因素估计了工人与肺部相关的疾病风险。
工人的暴露分为四级；在维护车间的焊工中，暴露最高，最高锰和铁暴露为 4 级，最高铬暴露为 3 级。亚组分析发现，与非焊工相比，焊工患肺部相关疾病的风险为 2.17 < ，男性焊工患肺部疾病的风险为 2.24 < ，非焊工。与非焊工相比，吸烟焊工患肺部相关疾病的发病率高 2.44 < 。总工龄作为肺部相关疾病风险的独立保护因素为 0.72 < 。作为一个独立的危险因素，高-高和高-低暴露的肺部相关疾病风险分别为 5.39 < 和 2.17 < 。
高焊接烟尘暴露是工人肺部相关疾病的重要危险因素。
