Yi Ooi Shin, Huan Khor Yek, Har Loo Chai, Ali Norazlima Mohd, Chiang Tan Wooi
Department of Dermatology, Hospital Pulau Pinang, Penang, Malaysia.
Indian J Dermatol. 2022 Mar-Apr;67(2):205. doi: 10.4103/ijd.ijd_754_21.
Genital psoriasis is often under-recognized and the exact burden is unknown in Malaysia.
To identify the prevalence of genital psoriasis, its clinical features, risk factors, and impact on quality of life and sexual health.
This prospective, observational study was conducted in the dermatology clinic of our hospital from 1 September 2020 until 31 March 2021, involving all adult patients with psoriasis. The genital examination was performed and the subjects were interviewed using questionnaires.
A total of 262 patients were recruited, with a male to female ratio of 1.5:1 (mean age of 51 years old). They comprised 42.0% Chinese, followed by 36.6% of Malay, 21.4% of Indians and others. Up to 46.1% of patients had a current or history of genital psoriasis. The most common area involved for males was the scrotum (44.1%) and labia majora (62.5%) for female patients. Itching (79.2%) was the most frequent symptom encountered. Chinese patients had 2.67 times odd (CI 1.55-4.61) of having genital psoriasis compared to non-Chinese patients. Other independent risk factors included flexural involvement, male gender, and Type 1 psoriasis. Genital psoriasis was associated with greater impairment on quality of life and sexual health (mean total Dermatology Life Quality Index: 8.8 vs 6.5, = 0.006), International Index of Erectile Function (mean: 48.5 vs 57.0, = 0.011) and revised version of Female Sexual Distress Scales (mean: 20.7 vs 11.4, = 0.022).
Genital psoriasis is common and it has a profound impact on patients.
生殖器银屑病在马来西亚常常未得到充分认识，其确切负担尚不清楚。
确定生殖器银屑病的患病率、临床特征、危险因素以及对生活质量和性健康的影响。
这项前瞻性观察性研究于2020年9月1日至2021年3月31日在我院皮肤科门诊进行，纳入所有成年银屑病患者。进行生殖器检查，并使用问卷对受试者进行访谈。
共招募了262名患者，男女比例为1.5:1（平均年龄51岁）。他们中42.0%为华裔，其次是36.6%的马来裔、21.4%的印度裔及其他族裔。高达46.1%的患者有生殖器银屑病的现患或病史。男性最常受累的部位是阴囊（44.1%），女性患者为大阴唇（62.5%）。瘙痒（79.2%）是最常见的症状。与非华裔患者相比，华裔患者患生殖器银屑病的几率高出2.67倍（可信区间1.55 - 4.61）。其他独立危险因素包括屈侧受累、男性性别和1型银屑病。生殖器银屑病与生活质量和性健康的更大损害相关（平均皮肤病生活质量指数：8.8对6.5，P = 0.006）、国际勃起功能指数（平均：48.5对57.0，P = 0.011）以及女性性困扰量表修订版（平均：20.7对11.4，P = 0.022）。
生殖器银屑病很常见，对患者有深远影响。
