Creydt Marina, Fischer Markus
Hamburg School of Food Science - Institute of Food Chemistry, University of Hamburg, Hamburg, Germany.
Electrophoresis. 2022 Dec;43(23-24):2334-2350. doi: 10.1002/elps.202200126. Epub 2022 Oct 6.
The analytical requirements for food testing have increased significantly in recent years. On the one hand, because food fraud is becoming an ever-greater challenge worldwide, and on the other hand because food safety is often difficult to monitor due to the far-reaching trade chains. In addition, the expectations of consumers on the quality of food have increased, and they are demanding extensive information. Cutting-edge analytical methods are required to meet these demands. In this context, non-targeted metabolomics strategies using mass and nuclear magnetic resonance spectrometers (mass spectrometry [MS]) have proven to be very suitable. MS-based approaches are of particular importance as they provide a comparatively high analytical coverage of the metabolome. Accordingly, the efficiency to address even challenging issues is high. A variety of hardware developments, which are explained in this review, have contributed to these advances. In addition, the potential of future developments is highlighted, some of which are currently not yet commercially available or only used to a comparatively small extent but are expected to gain in importance in the coming years.
近年来,食品检测的分析要求显著提高。一方面,因为食品欺诈在全球范围内正成为一个日益严峻的挑战,另一方面因为由于贸易链广泛,食品安全往往难以监测。此外,消费者对食品质量的期望提高了,他们要求获得广泛的信息。需要前沿的分析方法来满足这些需求。在这种背景下,使用质谱仪和核磁共振光谱仪的非靶向代谢组学策略已被证明非常合适。基于质谱的方法尤为重要,因为它们能提供相对较高的代谢组分析覆盖率。因此,解决甚至是具有挑战性问题的效率很高。本综述中解释的各种硬件发展促成了这些进展。此外,还强调了未来发展的潜力,其中一些目前尚未商业化或使用程度相对较小,但预计在未来几年将变得更加重要。