新型抗生素SF2415的研究。I. 分类学、发酵、分离、理化性质及生物活性

Studies on new antibiotics SF2415. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.

作者信息

Shomura T, Gomi S, Ito M, Yoshida J, Tanaka E, Amano S, Watabe H, Ohuchi S, Itoh J, Sezaki M

出版信息

J Antibiot (Tokyo). 1987 Jun;40(6):732-9. doi: 10.7164/antibiotics.40.732.

DOI:10.7164/antibiotics.40.732

Abstract

A new species of Streptomyces is described for which the name Streptomyces aculeolatus is proposed. The organism produces new antibiotics SF2415A1, A2, A3, B1, B2 and B3 active against Gram-positive bacteria. Empirical molecular formulae of the antibiotics SF2415A1, A2, A3, B1, B2 and B3 were determined to be C26H31N2O5Cl, C26H30N2O5, C26H30N2O5Cl2, C26H33O5Cl, C26H32O5 and C26H32O5Cl2, respectively.

摘要

描述了一种链霉菌新物种，并提议将其命名为尖刺链霉菌。该微生物产生了对革兰氏阳性菌有活性的新型抗生素SF2415A1、A2、A3、B1、B2和B3。抗生素SF2415A1、A2、A3、B1、B2和B3的经验分子式分别确定为C26H31N2O5Cl、C26H30N2O5、C26H30N2O5Cl2、C26H33O5Cl、C26H32O5和C26H32O5Cl2。