Gomi S, Ohuchi S, Sasaki T, Itoh J, Sezaki M
J Antibiot (Tokyo). 1987 Jun;40(6):740-9. doi: 10.7164/antibiotics.40.740.
Structures of new antibiotics SF2415A1, A2, A3, B1, B2 and B3 were deduced from spectroscopic analyses and degradation studies. The structure of SF2415A3, which has the most antibacterial activity, was proposed to be 3,4a-dichloro-9-diazo-3,4, 4a,10a-tetrahydro-6-hydroxy-2,2,7-trimethyl-10a-[(E)-3,7-dimethyl- 2,6-octadienyl]-(2H,9H)naphtho-[2,3-b]pyran-5,8,10-trione. All of antibiotics SF2415 have a semi-naphthoquinone structure.
通过光谱分析和降解研究推导了新型抗生素SF2415A1、A2、A3、B1、B2和B3的结构。具有最强抗菌活性的SF2415A3的结构被认为是3,4a-二氯-9-重氮基-3,4,4a,10a-四氢-6-羟基-2,2,7-三甲基-10a-[(E)-3,7-二甲基-2,6-辛二烯基]-(2H,9H)萘并-[2,3-b]吡喃-5,8,10-三酮。所有的抗生素SF2415都具有半萘醌结构。
