Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.
The Tokyo Foundation for Policy Research, Tokyo, Japan.
BMJ Open. 2022 Sep 20;12(9):e061444. doi: 10.1136/bmjopen-2022-061444.
The Tokyo 2020 Summer Olympic Games (23 July-8 August 2021) were held in the middle of Japan's fifth wave of COVID-19, when the number of cases was on the rise, and coincided with the fourth state of emergency implemented by the host city, Tokyo.
This study aimed to assess whether the hosting of the Games was associated with a change in the number of COVID-19 cases in Japan using a synthetic control method.
A weighted average of control countries with a variety of predictors was used to estimate the counterfactual trajectory of daily COVID-19 cases per 1 000 000 population in the absence of the Games in Japan. Outcome and predictor data were extracted using official and open sources spanning several countries. The predictors comprise the most recent country-level annual or daily data accessible during the Games, including the stringency of the government's COVID-19 response, testing capacity and vaccination capacity; human mobility index; electoral democracy index and demographic, socioeconomic, health and weather information. After excluding countries with missing data, 42 countries were ultimately used as control countries.
The number of observed cases per 1 000 000 population on the last day of the Games was 109.2 (7-day average), which was 115.7% higher than the counterfactual trajectory comprising 51.0 confirmed cases per 1 000 000 population. During the Olympic period (since 23 July), the observed cumulative number of cases was 61.0% higher than the counterfactual trajectory, comprising 143 072 and 89 210 confirmed cases (p=0.023), respectively. The counterfactual trajectory lagged 10 days behind the observed trends.
Given the increasing likelihood that new emerging infectious diseases will be reported in the future, we believe that the results of this study should serve as a sentinel warning for upcoming mega-events during COVID-19 and future pandemics.
东京 2020 年夏季奥运会(2021 年 7 月 23 日至 8 月 8 日)在日本第五波 COVID-19 疫情期间举行,当时病例数呈上升趋势,恰逢主办城市东京第四次实施紧急状态。
本研究旨在使用合成控制法评估举办奥运会是否与日本 COVID-19 病例数的变化相关。
使用多种预测因素的控制国家的加权平均值来估计日本在没有奥运会的情况下,每 100 万人口的 COVID-19 病例的每日估计反事实轨迹。使用官方和开放来源提取结果和预测数据,涵盖多个国家。预测因素包括在奥运会期间可获得的最新国家层面年度或每日数据,包括政府 COVID-19 应对措施的严格程度、检测能力和疫苗接种能力;人口流动指数;选举民主指数以及人口统计学、社会经济、健康和天气信息。排除缺失数据的国家后,最终有 42 个国家被用作控制国家。
奥运会最后一天每 100 万人口的观察病例数为 109.2(7 天平均值),比包括每 100 万人口 51.0 例确诊病例的反事实轨迹高出 115.7%。在奥运会期间(自 7 月 23 日以来),观察到的累计病例数比反事实轨迹高出 61.0%,包括 143072 例和 89210 例确诊病例(p=0.023)。反事实轨迹比观察趋势滞后 10 天。
鉴于未来可能会报告新出现的传染病,我们认为本研究的结果应该为未来 COVID-19 和未来大流行期间即将举行的大型活动提供预警。