Katila M L, Mäntjärvi R A
Clin Allergy. 1978 Nov;8(6):581-7. doi: 10.1111/j.1365-2222.1978.tb01512.x.
Precipitating antibodies towards antigens associated with farmer's lung disease were studied in Finnish dairy farming and non-farming rural populations and the results were compared to those of serum samples of patients suspected of having a fungal allergy. The antigen panel consisted of Aspergillus fumigatus, Micropolyspora faeni and Thermoactinomyces vulgaris. All three microbes seemed to be important environmental inducers of antibody formation. The prevalence of antibodies towards all of them was higher in the patient group. The presence of A. fumigatus and T. vulgaris antibodies correlated best with the occurrence of respiratory disease. The difference in M. faeni antibody prevalence between patients and the control group was less significant. The results suggest that in Finland the relative importance of those microorganisms associated with farmer's lung disease may be different from that reported from other countries.
在芬兰奶农和非农业农村人口中研究了针对与农民肺疾病相关抗原的沉淀抗体，并将结果与疑似患有真菌过敏症患者的血清样本结果进行了比较。抗原组包括烟曲霉、嗜热放线菌和普通嗜热放线菌。所有这三种微生物似乎都是抗体形成的重要环境诱导因素。患者组中针对所有这些微生物的抗体流行率更高。烟曲霉和普通嗜热放线菌抗体的存在与呼吸系统疾病的发生相关性最佳。患者与对照组之间嗜热放线菌抗体流行率的差异不太显著。结果表明，在芬兰，与农民肺疾病相关的那些微生物的相对重要性可能与其他国家报道的不同。
