Lemseffer Yassir, Terret Marie-Emilie, Campillo Clément, Labrune Elsa
Hospices Civils de Lyon, Service de Médecine de la Reproduction, 59 Bd. Pinel, 69500 Bron, France.
Faculté de Médecine, Université Claude Bernard, Lyon 01, 8 Av. Rockefeller, 69008 Lyon, France.
Biomedicines. 2022 Sep 4;10(9):2184. doi: 10.3390/biomedicines10092184.
The rate of infertility continues to rise in the world for several reasons, including the age of conception and current lifestyle. We list in this paper potential non-invasive and invasive techniques to assess oocyte quality. We searched the database PubMed using the terms "oocytes AND quality AND evaluation". In the first part, we study the morphological criteria, compartment by compartment, to then focus in a second part on more objective techniques such as genetics, molecular, apoptosis, or human follicular fluid that contain biologically active molecules. The main criteria used to assess oocyte quality are morphological; however, several other techniques have been studied in women to improve oocyte quality assessment, but most of them are invasive and not usable in routine.
由于多种原因,全球不孕症的发生率持续上升,这些原因包括受孕年龄和当前的生活方式。在本文中,我们列出了评估卵母细胞质量的潜在非侵入性和侵入性技术。我们使用“卵母细胞 AND 质量 AND 评估”等术语在PubMed数据库中进行了搜索。在第一部分,我们逐部分研究形态学标准,然后在第二部分重点关注更客观的技术,如遗传学、分子学、细胞凋亡或含有生物活性分子的人卵泡液。评估卵母细胞质量的主要标准是形态学标准;然而,已经在女性中研究了其他几种技术以改善卵母细胞质量评估,但其中大多数是侵入性的,无法在常规中使用。