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下颌骨朗格汉斯细胞组织细胞增多症

Langerhans Cell Histiocytosis of the Mandible.

作者信息

Padmanaban Kamalakannan, Kamalakaran Arunkumar, Raghavan Priyadharshini, Palani Triveni, Rajiah Davidson

机构信息

Oral and Maxillofacial Surgery, Tamilnadu Government Dental College and Hospital, Chennai, IND.

出版信息

Cureus. 2022 Aug 21;14(8):e28222. doi: 10.7759/cureus.28222. eCollection 2022 Aug.

Abstract

The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a reliable diagnosis without a thorough pathological examination is challenging. This report describes a case of eosinophilic granuloma of the mandible in a nine-year-old child with characteristic radiological, histopathological, and immunohistochemical features.

摘要

一种名为朗格汉斯细胞组织细胞增多症的罕见疾病,多见于儿童和年轻人,由朗格汉斯细胞的克隆性增殖引起。即使破坏性骨病变的临床体征和影像学证据可能引发对该疾病的怀疑,但在没有全面病理检查的情况下做出可靠诊断仍具有挑战性。本报告描述了一例9岁儿童下颌骨嗜酸性肉芽肿病例,具有典型的放射学、组织病理学和免疫组化特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91cf/9486456/bc455dfaa97d/cureus-0014-00000028222-i09.jpg

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