Floyd R, Gryson R, Mockler D, Gibney J, Duggan S N, Behan L A
Department of Endocrinology, Robert Graves Institute of Endocrinology, Tallaght University Hospital, Dublin, Ireland.
Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Int J Endocrinol. 2022 Sep 16;2022:2830545. doi: 10.1155/2022/2830545. eCollection 2022.
2662 papers were identified with 37 selected for full-text review and one paper meeting criteria for inclusion. Ramadan fasting was the only time-restricted eating regimen trialled in this population with no strong evidence of a significant effect on insulin levels.
As the systematic review retrieved only one study investigating time-restricted eating to reduce insulin in patients with PCOS, there is no evidence to suggest that this intervention is effective. From the narrative review, based on studies in other patient groups, time-restricted eating could improve insulin resistance in those with PCOS; however, well-designed studies are required before this intervention can be recommended.
共识别出2662篇论文，其中37篇被选作全文审查，1篇符合纳入标准。斋月禁食是该人群中唯一试验过的限时饮食方案，没有有力证据表明其对胰岛素水平有显著影响。
由于该系统评价仅检索到一项关于限时饮食对多囊卵巢综合征患者胰岛素影响的研究，尚无证据表明这种干预措施有效。从基于其他患者群体研究的叙述性综述来看，限时饮食可能改善多囊卵巢综合征患者的胰岛素抵抗；然而，在推荐这种干预措施之前，需要进行精心设计的研究。
