Chatzis Dimitrios G, Magounaki Kalliopi, Pantazopoulos Ioannis, Bhaskar Sonu Menachem Maimonides
Medical School, European University Cyprus, Nicosia 2404, Cyprus.
Department of Internal Medicine, KAT General Hospital, Athens 14561, Greece.
World J Clin Cases. 2022 Sep 26;10(27):9602-9610. doi: 10.12998/wjcc.v10.i27.9602.
The current coronavirus disease 2019 (COVID-19) pandemic has had devastating impact on populations around the world. The high mortality rates in patients with COVID-19 has been attributed to the influence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), its causative viral agent, on several physiological systems in human body, including the respiratory, cardiovascular, and neurological systems. There is emerging evidence on propensity of this virus to attack cardiovascular system. However, various pathophysiological mechanisms by which SARS-CoV-2 interacts with cardiovascular system and leads to high morbidity and mortality, including cardiovascular complications, are poorly understood. This mini review aims to provide an update on the current knowledge and perspectives on areas of future research.
当前的2019冠状病毒病(COVID-19)大流行对世界各地的人群产生了毁灭性影响。COVID-19患者的高死亡率归因于其致病病毒病原体严重急性呼吸综合征冠状病毒2(SARS-CoV-2)对人体多个生理系统的影响,包括呼吸、心血管和神经系统。越来越多的证据表明这种病毒有攻击心血管系统的倾向。然而,SARS-CoV-2与心血管系统相互作用并导致高发病率和死亡率(包括心血管并发症)的各种病理生理机制仍知之甚少。本综述旨在提供有关当前知识以及未来研究领域观点的最新信息。