Thushara Nadini, Malawiarachchi Prashantha, Samarakoon Sameera R, Godakumbura Pahan I
Department of Chemistry, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, 10250 Sri Lanka.
Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Colombo, Sri Lanka.
J Food Sci Technol. 2022 Oct;59(10):3745-3753. doi: 10.1007/s13197-021-05341-9. Epub 2022 Jan 26.
Four Sri Lankan porridges including madathawalu (MWP), kaluheenati (KHP), mixed rice of sudu heenati, goda heenati, masuran, and dikwee (MXP) and special traditional porridge (STP) were screened for in vitro glycemic indices (GI), α-amylase inhibition and anti-glycation activities. All four porridges had the medium GI values, those were in the range of 40.5 ± 4 to 63.9 ± 2. The highest antiglycation activity was reported for MWP demonstrating IC of 228.20 ± 4.20 µg/mL. In relation to the α-amylase inhibition activity, the porridge extracts of MWP and STP low IC values (117.54 ± 1.92 µg/mL and 128.75 ± 5.91 µg/mL) showed their high capability to inhibit α-amylase enzyme. Due to the medium to low GI values and high antiglycation and α-amylase inhibition activities, traditional rice based porridges can be considered as effective for the prevention of diabetic conditions as well as from various complications in diabetic patients. Anticancer activity against human lung and HeLa cell lines revealed that KHP and MXP exhibited anticancer activity (IC of 274.6 μg/mL and 940.2 μg/mL respectively) against HeLa- human cervical cancer cells. In conclusion, porridge composites prepared using Sri Lankan traditional rice helped to eliminate or notably reduce nutrient deficiencies, and it provided numerous health benefits and economical gains.
对四种斯里兰卡粥进行了体外血糖指数(GI)、α-淀粉酶抑制和抗糖化活性的筛选,这四种粥分别是马德塔瓦卢粥(MWP)、卡卢赫纳蒂粥(KHP)、由苏杜赫纳蒂、戈达赫纳蒂、马苏兰和迪奎混合而成的米饭粥(MXP)以及特殊传统粥(STP)。所有四种粥的血糖指数值均为中等,范围在40.5±4至63.9±2之间。据报道,MWP的抗糖化活性最高,其半数抑制浓度(IC)为228.20±4.20μg/mL。关于α-淀粉酶抑制活性,MWP和STP的粥提取物的低半数抑制浓度值(分别为117.54±1.92μg/mL和128.75±5.91μg/mL)表明它们具有很高的抑制α-淀粉酶的能力。由于血糖指数值为中等至低,且具有较高的抗糖化和α-淀粉酶抑制活性,基于传统大米的粥可被认为对预防糖尿病病情以及糖尿病患者的各种并发症有效。对人肺癌细胞系和人宫颈癌细胞系(HeLa)的抗癌活性研究表明,KHP和MXP对HeLa人宫颈癌细胞具有抗癌活性(IC分别为274.6μg/mL和940.2μg/mL)。总之,用斯里兰卡传统大米制备的粥类复合物有助于消除或显著减少营养缺乏,并且提供了众多健康益处和经济效益。