Polit Francesca, Bahmad Hisham F, Wahi Jessica, Deb Arunima, Newsome Kevin, Howard Lydia, Poppiti Robert, Ben-David Kfir, Alghamdi Sarah
Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL, USA.
Department of General Surgery, Mount Sinai Medical Center, Miami Beach, FL, USA.
J Surg Case Rep. 2022 Sep 28;2022(9):rjac458. doi: 10.1093/jscr/rjac458. eCollection 2022 Sep.
Squamous cell carcinoma (SCC) arising in a Zenker diverticulum (ZD) is an extremely rare entity. Approximately 50 cases have been reported worldwide. We report a case of a 74-year-old man who presented to our institution with chronic regurgitation, dysphagia and halitosis. The patient was initially seen in 2015 at which point he reported a 10-year history of these symptoms and was diagnosed with ZD. A barium swallow was done revealing a large posterior esophageal diverticulum with significant residual contrast within the diverticulum lumen. Given these findings, he was taken for open surgical excision where a SCC was identified. Although it is extremely rare for a SCC to occur in a ZD, patients with ZD must undergo regular surveillance endoscopy of the esophagus and the diverticulum itself to identify any suspicious mass or lesion arising in within.
起源于Zenker憩室（ZD）的鳞状细胞癌（SCC）是一种极其罕见的疾病。全球范围内报告的病例约有50例。我们报告一例74岁男性患者，他因慢性反流、吞咽困难和口臭前来我院就诊。该患者最初于2015年就诊，当时他自述有这些症状已达10年，被诊断为ZD。进行了吞钡检查，发现食管后有一个大憩室，憩室内有大量造影剂残留。鉴于这些发现，他接受了开放性手术切除，术中发现了SCC。虽然SCC在ZD中极为罕见，但ZD患者必须定期接受食管及憩室本身的内镜检查，以发现其中出现的任何可疑肿块或病变。
