Lin Bobo, Huang Gangliang
Key Laboratory of Carbohydrate Science and Engineering, Chongqing Key Laboratory of Inorganic Functional Materials, Chongqing Normal University, Chongqing 401331, China.
Food Chem X. 2022 Jul 8;15:100388. doi: 10.1016/j.fochx.2022.100388. eCollection 2022 Oct 30.
Fermentum is a common unicellular fungus with many biological activities attributed to β-polysaccharides. Different in vivo and in vivo experimental studies have long proven that fermentum β-polysaccharides have antioxidant, anti-tumor, and fungal toxin adsorption properties. However, there are many uncertainties regarding the relationship between the structure and biological activity of fermentum β-polysaccharides, and a systematic summary of fermentum β-polysaccharides is still lacking. Herein, we reviewed the research progress about the extraction, structure and modification, structure-activity relationship, activity and application of fermentum β-polysaccharides, compared the extraction methods of fermentum β-polysaccharide, and paid special attention to the structure-activity relationship and application of fermentum β-polysaccharide, which provided a strong basis for the development and application of fermentum β-polysaccharide.
发酵菌是一种常见的单细胞真菌,其β-多糖具有多种生物活性。长期以来,不同的体内和体外实验研究证明,发酵菌β-多糖具有抗氧化、抗肿瘤和真菌毒素吸附特性。然而,关于发酵菌β-多糖的结构与生物活性之间的关系仍存在许多不确定性,且目前仍缺乏对发酵菌β-多糖的系统总结。在此,我们综述了发酵菌β-多糖在提取、结构与修饰、构效关系、活性及应用方面的研究进展,比较了发酵菌β-多糖的提取方法,并特别关注了发酵菌β-多糖的构效关系及应用,为发酵菌β-多糖的开发与应用提供了有力依据。