Department of Neurology, NYU Grossman School of Medicine, New York, NY, USA.
Neuroscience Institute, NYU Langone Medical Center, New York, NY, USA.
Nat Commun. 2022 Oct 12;13(1):6000. doi: 10.1038/s41467-022-33536-x.
Decades of rodent research have established the role of hippocampal sharp wave ripples (SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in humans have suggested their role in episodic and semantic memory. Yet, common standards for recording, detection, and reporting do not exist. Here, we outline the methodological challenges involved in detecting ripple events and offer practical recommendations to improve separation from other high-frequency oscillations. We argue that shared experimental, detection, and reporting standards will provide a solid foundation for future translational discovery.
数十年的啮齿动物研究已经确定了海马体尖波涟漪（SPW-R）在巩固和引导经验方面的作用。最近，对人类的颅内记录表明它们在情景和语义记忆中的作用。然而，目前还没有记录、检测和报告的通用标准。在这里，我们概述了检测涟漪事件所涉及的方法学挑战，并提供了改善与其他高频振荡分离的实用建议。我们认为，共享的实验、检测和报告标准将为未来的转化发现提供坚实的基础。
Zotero 插件
